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762 results

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EDEM3 Modulates Plasma Triglyceride Level through Its Regulation of LRP1 Expression.
Xu YX, Peloso GM, Nagai TH, Mizoguchi T, Deik A, Bullock K, Lin H, Musunuru K, Yang Q, Vasan RS, Gerszten RE, Clish CB, Rader D, Kathiresan S. Xu YX, et al. Among authors: mizoguchi t. iScience. 2020 Apr 24;23(4):100973. doi: 10.1016/j.isci.2020.100973. Epub 2020 Mar 11. iScience. 2020. PMID: 32213464 Free PMC article.
Endothelial ARHGEF26 is an angiogenic factor promoting VEGF signalling.
Zhu QM, MacDonald BT, Mizoguchi T, Chaffin M, Leed A, Arduini A, Malolepsza E, Lage K, Kaushik VK, Kathiresan S, Ellinor PT. Zhu QM, et al. Among authors: mizoguchi t. Cardiovasc Res. 2022 Oct 21;118(13):2833-2846. doi: 10.1093/cvr/cvab344. Cardiovasc Res. 2022. PMID: 34849650 Free PMC article.
In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.
Musunuru K, Chadwick AC, Mizoguchi T, Garcia SP, DeNizio JE, Reiss CW, Wang K, Iyer S, Dutta C, Clendaniel V, Amaonye M, Beach A, Berth K, Biswas S, Braun MC, Chen HM, Colace TV, Ganey JD, Gangopadhyay SA, Garrity R, Kasiewicz LN, Lavoie J, Madsen JA, Matsumoto Y, Mazzola AM, Nasrullah YS, Nneji J, Ren H, Sanjeev A, Shay M, Stahley MR, Fan SHY, Tam YK, Gaudelli NM, Ciaramella G, Stolz LE, Malyala P, Cheng CJ, Rajeev KG, Rohde E, Bellinger AM, Kathiresan S. Musunuru K, et al. Among authors: mizoguchi t. Nature. 2021 May;593(7859):429-434. doi: 10.1038/s41586-021-03534-y. Epub 2021 May 19. Nature. 2021. PMID: 34012082
Coronary Disease Association With ADAMTS7 Is Due to Protease Activity.
Mizoguchi T, MacDonald BT, Bhandary B, Popp NR, Laprise D, Arduini A, Lai D, Zhu QM, Xing Y, Kaushik VK, Kathiresan S, Ellinor PT. Mizoguchi T, et al. Circ Res. 2021 Aug 6;129(4):458-470. doi: 10.1161/CIRCRESAHA.121.319163. Epub 2021 Jun 28. Circ Res. 2021. PMID: 34176299 Free PMC article.
Regulatory/effector T-cell ratio is reduced in coronary artery disease.
Emoto T, Sasaki N, Yamashita T, Kasahara K, Yodoi K, Sasaki Y, Matsumoto T, Mizoguchi T, Hirata K. Emoto T, et al. Among authors: mizoguchi t. Circ J. 2014;78(12):2935-41. doi: 10.1253/circj.cj-14-0644. Epub 2014 Oct 18. Circ J. 2014. PMID: 25327882 Free article.
Gut Microbiome and Plasma Microbiome-Related Metabolites in Patients With Decompensated and Compensated Heart Failure.
Hayashi T, Yamashita T, Watanabe H, Kami K, Yoshida N, Tabata T, Emoto T, Sasaki N, Mizoguchi T, Irino Y, Toh R, Shinohara M, Okada Y, Ogawa W, Yamada T, Hirata KI. Hayashi T, et al. Among authors: mizoguchi t. Circ J. 2018 Dec 25;83(1):182-192. doi: 10.1253/circj.CJ-18-0468. Epub 2018 Nov 29. Circ J. 2018. PMID: 30487369 Free article. Clinical Trial.
762 results