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CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.
Han K, Pierce SE, Li A, Spees K, Anderson GR, Seoane JA, Lo YH, Dubreuil M, Olivas M, Kamber RA, Wainberg M, Kostyrko K, Kelly MR, Yousefi M, Simpkins SW, Yao D, Lee K, Kuo CJ, Jackson PK, Sweet-Cordero A, Kundaje A, Gentles AJ, Curtis C, Winslow MM, Bassik MC. Han K, et al. Among authors: gentles aj. Nature. 2020 Apr;580(7801):136-141. doi: 10.1038/s41586-020-2099-x. Epub 2020 Mar 11. Nature. 2020. PMID: 32238925 Free PMC article.
Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA.
Zhang W, Li I, Reticker-Flynn NE, Good Z, Chang S, Samusik N, Saumyaa S, Li Y, Zhou X, Liang R, Kong CS, Le QT, Gentles AJ, Sunwoo JB, Nolan GP, Engleman EG, Plevritis SK. Zhang W, et al. Among authors: gentles aj. Nat Methods. 2022 Jun;19(6):759-769. doi: 10.1038/s41592-022-01498-z. Epub 2022 Jun 2. Nat Methods. 2022. PMID: 35654951 Free PMC article.
Genomics. Annotation of the Drosophila genome.
Karlin S, Bergman A, Gentles AJ. Karlin S, et al. Among authors: gentles aj. Nature. 2001 May 17;411(6835):259-60. doi: 10.1038/35077152. Nature. 2001. PMID: 11357119 No abstract available.
Robust enumeration of cell subsets from tissue expression profiles.
Newman AM, Liu CL, Green MR, Gentles AJ, Feng W, Xu Y, Hoang CD, Diehn M, Alizadeh AA. Newman AM, et al. Among authors: gentles aj. Nat Methods. 2015 May;12(5):453-7. doi: 10.1038/nmeth.3337. Epub 2015 Mar 30. Nat Methods. 2015. PMID: 25822800 Free PMC article.
Determining cell type abundance and expression from bulk tissues with digital cytometry.
Newman AM, Steen CB, Liu CL, Gentles AJ, Chaudhuri AA, Scherer F, Khodadoust MS, Esfahani MS, Luca BA, Steiner D, Diehn M, Alizadeh AA. Newman AM, et al. Among authors: gentles aj. Nat Biotechnol. 2019 Jul;37(7):773-782. doi: 10.1038/s41587-019-0114-2. Epub 2019 May 6. Nat Biotechnol. 2019. PMID: 31061481 Free PMC article.
Systems biology: confronting the complexity of cancer.
Gentles AJ, Gallahan D. Gentles AJ, et al. Cancer Res. 2011 Sep 15;71(18):5961-4. doi: 10.1158/0008-5472.CAN-11-1569. Epub 2011 Sep 6. Cancer Res. 2011. PMID: 21896642 Free PMC article.
108 results