Metformin increases glucose uptake and acts renoprotectively by reducing SHIP2 activity.
Polianskyte-Prause Z, Tolvanen TA, Lindfors S, Dumont V, Van M, Wang H, Dash SN, Berg M, Naams JB, Hautala LC, Nisen H, Mirtti T, Groop PH, Wähälä K, Tienari J, Lehtonen S.
Polianskyte-Prause Z, et al. Among authors: dumont v.
FASEB J. 2019 Feb;33(2):2858-2869. doi: 10.1096/fj.201800529RR. Epub 2018 Oct 15.
FASEB J. 2019.
PMID: 30321069
Free PMC article.
Our data unravel a novel molecular mechanism by which metformin enhances glucose uptake and acts renoprotectively by reducing SHIP2 activity.-Polianskyte-Prause, Z., Tolvanen, T. A., Lindfors, S., Dumont, V., Van, M., Wang, H., Dash, S. N., Berg, M., Naams, J.-B., H …
Our data unravel a novel molecular mechanism by which metformin enhances glucose uptake and acts renoprotectively by reducing SHIP2 activity …