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Obesity Is Associated With Low NAD(+)/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins.
Jukarainen S, Heinonen S, Rämö JT, Rinnankoski-Tuikka R, Rappou E, Tummers M, Muniandy M, Hakkarainen A, Lundbom J, Lundbom N, Kaprio J, Rissanen A, Pirinen E, Pietiläinen KH. Jukarainen S, et al. Among authors: pirinen e. J Clin Endocrinol Metab. 2016 Jan;101(1):275-83. doi: 10.1210/jc.2015-3095. Epub 2015 Nov 17. J Clin Endocrinol Metab. 2016. PMID: 26574954
Weight Loss Is Associated With Increased NAD(+)/SIRT1 Expression But Reduced PARP Activity in White Adipose Tissue.
Rappou E, Jukarainen S, Rinnankoski-Tuikka R, Kaye S, Heinonen S, Hakkarainen A, Lundbom J, Lundbom N, Saunavaara V, Rissanen A, Virtanen KA, Pirinen E, Pietiläinen KH. Rappou E, et al. Among authors: pirinen e. J Clin Endocrinol Metab. 2016 Mar;101(3):1263-73. doi: 10.1210/jc.2015-3054. Epub 2016 Jan 13. J Clin Endocrinol Metab. 2016. PMID: 26760174 Clinical Trial.
Adipose tissue mitochondrial capacity associates with long-term weight loss success.
Jokinen R, Rinnankoski-Tuikka R, Kaye S, Saarinen L, Heinonen S, Myöhänen M, Rappou E, Jukarainen S, Rissanen A, Pessia A, Velagapudi V, Virtanen KA, Pirinen E, Pietiläinen KH. Jokinen R, et al. Among authors: pirinen e. Int J Obes (Lond). 2018 Apr;42(4):817-825. doi: 10.1038/ijo.2017.299. Epub 2017 Dec 5. Int J Obes (Lond). 2018. PMID: 29203860 Clinical Trial.
Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.
Pirinen E, Kuulasmaa T, Pietilä M, Heikkinen S, Tusa M, Itkonen P, Boman S, Skommer J, Virkamäki A, Hohtola E, Kettunen M, Fatrai S, Kansanen E, Koota S, Niiranen K, Parkkinen J, Levonen AL, Ylä-Herttuala S, Hiltunen JK, Alhonen L, Smith U, Jänne J, Laakso M. Pirinen E, et al. Mol Cell Biol. 2007 Jul;27(13):4953-67. doi: 10.1128/MCB.02034-06. Epub 2007 May 7. Mol Cell Biol. 2007. PMID: 17485446 Free PMC article.
The activation of hepatic and muscle polyamine catabolism improves glucose homeostasis.
Koponen T, Cerrada-Gimenez M, Pirinen E, Hohtola E, Paananen J, Vuohelainen S, Tusa M, Pirnes-Karhu S, Heikkinen S, Virkamäki A, Uimari A, Alhonen L, Laakso M. Koponen T, et al. Among authors: pirinen e. Amino Acids. 2012 Feb;42(2-3):427-40. doi: 10.1007/s00726-011-1013-0. Epub 2011 Aug 4. Amino Acids. 2012. PMID: 21814795
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study.
Lapatto HAK, Kuusela M, Heikkinen A, Muniandy M, van der Kolk BW, Gopalakrishnan S, Pöllänen N, Sandvik M, Schmidt MS, Heinonen S, Saari S, Kuula J, Hakkarainen A, Tampio J, Saarinen T, Taskinen MR, Lundbom N, Groop PH, Tiirola M, Katajisto P, Lehtonen M, Brenner C, Kaprio J, Pekkala S, Ollikainen M, Pietiläinen KH, Pirinen E. Lapatto HAK, et al. Among authors: pirinen e. Sci Adv. 2023 Jan 13;9(2):eadd5163. doi: 10.1126/sciadv.add5163. Epub 2023 Jan 13. Sci Adv. 2023. PMID: 36638183 Free PMC article.
66 results