Lewis LD - Search Results

1

AMPK Activation by Metformin Promotes Survival of Dormant ER⁺ Breast Cancer Cells.

Hampsch RA, Wells JD, Traphagen NA, McCleery CF, Fields JL, Shee K, Dillon LM, Pooler DB, Lewis LD, Demidenko E, Huang YH, Marotti JD, Goen AE, Kinlaw WB, Miller TW. Hampsch RA, et al. Among authors: lewis ld. Clin Cancer Res. 2020 Jul 15;26(14):3707-3719. doi: 10.1158/1078-0432.CCR-20-0269. Epub 2020 Apr 22. Clin Cancer Res. 2020. PMID: 32321715 Free PMC article.

2

Oxygen consumption rates and oxygen concentration in molt-4 cells and their mtDNA depleted (rho0) mutants.

Shen J, Khan N, Lewis LD, Armand R, Grinberg O, Demidenko E, Swartz H. Shen J, et al. Among authors: lewis ld. Biophys J. 2003 Feb;84(2 Pt 1):1291-8. doi: 10.1016/S0006-3495(03)74944-3. Biophys J. 2003. PMID: 12547809 Free PMC article.

3

Modulation of cell cycle progression in human tumors: a pharmacokinetic and tumor molecular pharmacodynamic study of cisplatin plus the Chk1 inhibitor UCN-01 (NSC 638850).

Perez RP, Lewis LD, Beelen AP, Olszanski AJ, Johnston N, Rhodes CH, Beaulieu B, Ernstoff MS, Eastman A. Perez RP, et al. Among authors: lewis ld. Clin Cancer Res. 2006 Dec 1;12(23):7079-85. doi: 10.1158/1078-0432.CCR-06-0197. Clin Cancer Res. 2006. PMID: 17145831 Clinical Trial.

4

A comparison of the pharmacokinetics and pharmacodynamics of docetaxel between African-American and Caucasian cancer patients: CALGB 9871.

Lewis LD, Miller AA, Rosner GL, Dowell JE, Valdivieso M, Relling MV, Egorin MJ, Bies RR, Hollis DR, Levine EG, Otterson GA, Millard F, Ratain MJ; Cancer and Leukemia Group B. Lewis LD, et al. Clin Cancer Res. 2007 Jun 1;13(11):3302-11. doi: 10.1158/1078-0432.CCR-06-2345. Clin Cancer Res. 2007. PMID: 17545536

5

Conjugated linoleic acid (CLA) inhibits expression of the Spot 14 (THRSP) and fatty acid synthase genes and impairs the growth of human breast cancer and liposarcoma cells.

Donnelly C, Olsen AM, Lewis LD, Eisenberg BL, Eastman A, Kinlaw WB. Donnelly C, et al. Among authors: lewis ld. Nutr Cancer. 2009;61(1):114-22. doi: 10.1080/01635580802348666. Nutr Cancer. 2009. PMID: 19116881 Free PMC article.

6

A proof of principle clinical trial to determine whether conjugated linoleic acid modulates the lipogenic pathway in human breast cancer tissue.

McGowan MM, Eisenberg BL, Lewis LD, Froehlich HM, Wells WA, Eastman A, Kuemmerle NB, Rosenkrantz KM, Barth RJ Jr, Schwartz GN, Li Z, Tosteson TD, Beaulieu BB Jr, Kinlaw WB. McGowan MM, et al. Among authors: lewis ld. Breast Cancer Res Treat. 2013 Feb;138(1):175-83. doi: 10.1007/s10549-013-2446-9. Epub 2013 Feb 16. Breast Cancer Res Treat. 2013. PMID: 23417336 Free PMC article. Clinical Trial.

7

Tumor cell targeting by iron oxide nanoparticles is dominated by different factors in vitro versus in vivo.

NDong C, Tate JA, Kett WC, Batra J, Demidenko E, Lewis LD, Hoopes PJ, Gerngross TU, Griswold KE. NDong C, et al. Among authors: lewis ld. PLoS One. 2015 Feb 19;10(2):e0115636. doi: 10.1371/journal.pone.0115636. eCollection 2015. PLoS One. 2015. PMID: 25695795 Free PMC article.

8

Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha-Positive, PIK3CA-Mutant Breast Cancer.

Yang W, Hosford SR, Dillon LM, Shee K, Liu SC, Bean JR, Salphati L, Pang J, Zhang X, Nannini MA, Demidenko E, Bates D, Lewis LD, Marotti JD, Eastman AR, Miller TW. Yang W, et al. Among authors: lewis ld. Clin Cancer Res. 2016 May 1;22(9):2250-60. doi: 10.1158/1078-0432.CCR-15-2276. Epub 2016 Jan 5. Clin Cancer Res. 2016. PMID: 26733612 Free PMC article.

9

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer.

Hampsch RA, Shee K, Bates D, Lewis LD, Désiré L, Leblond B, Demidenko E, Stefan K, Huang YH, Miller TW. Hampsch RA, et al. Among authors: lewis ld. Oncotarget. 2017 Mar 28;8(13):21806-21817. doi: 10.18632/oncotarget.15586. Oncotarget. 2017. PMID: 28423521 Free PMC article.

10

An Inhibitor of Fatty Acid Synthase Thioesterase Domain with Improved Cytotoxicity against Breast Cancer Cells and Stability in Plasma.

Lupien LE, Dunkley EM, Maloy MJ, Lehner IB, Foisey MG, Ouellette ME, Lewis LD, Pooler DB, Kinlaw WB, Baures PW. Lupien LE, et al. Among authors: lewis ld. J Pharmacol Exp Ther. 2019 Oct;371(1):171-185. doi: 10.1124/jpet.119.258947. Epub 2019 Jul 12. J Pharmacol Exp Ther. 2019. PMID: 31300609 Free PMC article.

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