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Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium.
Portelli MA, Dijk FN, Ketelaar ME, Shrine N, Hankinson J, Bhaker S, Grotenboer NS, Obeidat M, Henry AP, Billington CK, Shaw D, Johnson SR, Pogson ZE, Fogarty A, McKeever TM, Nickle DC, Bossé Y, van den Berge M, Faiz A, Brouwer S, Vonk JM, de Vos P, Brandsma CA, Vermeulen CJ, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Blakey JD, Tobin MD, Postma DS, Hall IP, Wain LV, Nawijn MC, Brightling CE, Koppelman GH, Sayers I. Portelli MA, et al. Among authors: postma ds. JCI Insight. 2020 Apr 23;5(8):e132446. doi: 10.1172/jci.insight.132446. JCI Insight. 2020. PMID: 32324168 Free PMC article.
PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline.
Barton SJ, Koppelman GH, Vonk JM, Browning CA, Nolte IM, Stewart CE, Bainbridge S, Mutch S, Rose-Zerilli MJ, Postma DS, Maniatis N, Henry AP, Hall IP, Holgate ST, Tighe P, Holloway JW, Sayers I. Barton SJ, et al. Among authors: postma ds. J Allergy Clin Immunol. 2009 Jun;123(6):1391-400.e17. doi: 10.1016/j.jaci.2009.03.014. Epub 2009 May 13. J Allergy Clin Immunol. 2009. PMID: 19443020
Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma.
Dijk FN, Xu C, Melén E, Carsin AE, Kumar A, Nolte IM, Gruzieva O, Pershagen G, Grotenboer NS, Savenije OEM, Antó JM, Lavi I, Dobaño C, Bousquet J, van der Vlies P, van der Valk RJP, de Jongste JC, Nawijn MC, Guerra S, Postma DS, Koppelman GH. Dijk FN, et al. Among authors: postma ds. Eur Respir J. 2018 Mar 8;51(3):1701377. doi: 10.1183/13993003.01377-2017. Print 2018 Mar. Eur Respir J. 2018. PMID: 29519908 Free article.
A large-scale, consortium-based genomewide association study of asthma.
Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WOCM; GABRIEL Consortium. Moffatt MF, et al. N Engl J Med. 2010 Sep 23;363(13):1211-1221. doi: 10.1056/NEJMoa0906312. N Engl J Med. 2010. PMID: 20860503 Free PMC article.
E-cadherin: gatekeeper of airway mucosa and allergic sensitization.
Nawijn MC, Hackett TL, Postma DS, van Oosterhout AJ, Heijink IH. Nawijn MC, et al. Among authors: postma ds. Trends Immunol. 2011 Jun;32(6):248-55. doi: 10.1016/j.it.2011.03.004. Epub 2011 Apr 12. Trends Immunol. 2011. PMID: 21493142 Review.
Lung eQTLs to help reveal the molecular underpinnings of asthma.
Hao K, Bossé Y, Nickle DC, Paré PD, Postma DS, Laviolette M, Sandford A, Hackett TL, Daley D, Hogg JC, Elliott WM, Couture C, Lamontagne M, Brandsma CA, van den Berge M, Koppelman G, Reicin AS, Nicholson DW, Malkov V, Derry JM, Suver C, Tsou JA, Kulkarni A, Zhang C, Vessey R, Opiteck GJ, Curtis SP, Timens W, Sin DD. Hao K, et al. Among authors: postma ds. PLoS Genet. 2012;8(11):e1003029. doi: 10.1371/journal.pgen.1003029. Epub 2012 Nov 29. PLoS Genet. 2012. PMID: 23209423 Free PMC article.
897 results