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Recent approaches to gout drug discovery: an update.
Otani N, Ouchi M, Kudo H, Tsuruoka S, Hisatome I, Anzai N. Otani N, et al. Expert Opin Drug Discov. 2020 Aug;15(8):943-954. doi: 10.1080/17460441.2020.1755251. Epub 2020 Apr 24. Expert Opin Drug Discov. 2020. PMID: 32329387 Review.
[Disturbance of uric acid metabolism].
Ouchi M, Otani N, Anzai N. Ouchi M, et al. Among authors: otani n. Nihon Jinzo Gakkai Shi. 2015;57(4):766-73. Nihon Jinzo Gakkai Shi. 2015. PMID: 26126334 Japanese. No abstract available.
Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.
Mishima M, Hamada T, Maharani N, Ikeda N, Onohara T, Notsu T, Ninomiya H, Miyazaki S, Mizuta E, Sugihara S, Kato M, Ogino K, Kuwabara M, Hirota Y, Yoshida A, Otani N, Anzai N, Hisatome I. Mishima M, et al. Among authors: otani n. Drug Res (Stuttg). 2016 May;66(5):270-4. doi: 10.1055/s-0035-1569405. Epub 2016 Feb 24. Drug Res (Stuttg). 2016. PMID: 26909689
Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells.
Onohara T, Hisatome I, Kurata Y, Li P, Notsu T, Morikawa K, Otani N, Yoshida A, Iitsuka K, Kato M, Miake J, Ninomiya H, Higaki K, Shirayoshi Y, Nishihara T, Itoh T, Nakamura Y, Nishimura M. Onohara T, et al. Among authors: otani n. J Arrhythm. 2017 Jun;33(3):226-233. doi: 10.1016/j.joa.2016.09.003. Epub 2016 Oct 19. J Arrhythm. 2017. PMID: 28607619 Free PMC article.
Uric acid lowering in relation to HbA1c reductions with the SGLT2 inhibitor tofogliflozin.
Ouchi M, Oba K, Kaku K, Suganami H, Yoshida A, Fukunaka Y, Jutabha P, Morita A, Otani N, Hayashi K, Fujita T, Suzuki T, Yasutake M, Anzai N. Ouchi M, et al. Among authors: otani n. Diabetes Obes Metab. 2018 Apr;20(4):1061-1065. doi: 10.1111/dom.13170. Epub 2018 Jan 8. Diabetes Obes Metab. 2018. PMID: 29171930 Free PMC article.
Protective Effects of Topiroxostat on an Ischemia-Reperfusion Model of Rat Hearts.
Tanno S, Yamamoto K, Kurata Y, Adachi M, Inoue Y, Otani N, Mishima M, Yamamoto Y, Kuwabara M, Ogino K, Miake J, Ninomiya H, Shirayoshi Y, Okada F, Yamamoto K, Hisatome I. Tanno S, et al. Among authors: otani n. Circ J. 2018 Mar 23;82(4):1101-1111. doi: 10.1253/circj.CJ-17-1049. Epub 2018 Feb 28. Circ J. 2018. PMID: 29491325 Free article.
526 results