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An Alzheimer Disease Challenge Model: 24-Hour Sleep Deprivation in Healthy Volunteers, Impact on Working Memory, and Reversal Effect of Pharmacological Intervention: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
Chan Kwong A, Cassé-Perrot C, Costes-Salon MC, Jouve E, Lanteaume L, Audebert C, Rouby F, Lefebvre MN, Ranjeva JP, Beck A, Deplanque D, Ponchel A, Vervueren C, Truillet R, Babilon C, Auffret A, Richardson JC, Payoux P, Bartrés-Faz D, Blin O, Bordet R, Micallef J; Pharmacog Consortium. Chan Kwong A, et al. Among authors: lefebvre mn. J Clin Psychopharmacol. 2020 May/Jun;40(3):222-230. doi: 10.1097/JCP.0000000000001199. J Clin Psychopharmacol. 2020. PMID: 32332458 Clinical Trial.
Neurobehavioral and Cognitive Changes Induced by Hypoxia in Healthy Volunteers.
Lanteaume L, Cassé-Perrot C, Lefebvre MN, Audebert C, Deguil J, Auffret A, Otten L, Bartrés-Faz D, Blin O, Bordet R, Micallef J. Lanteaume L, et al. Among authors: lefebvre mn. CNS Neurol Disord Drug Targets. 2016;15(7):816-22. doi: 10.2174/1871527315666160518125612. CNS Neurol Disord Drug Targets. 2016. PMID: 26825090 Review.
Brain Networks are Independently Modulated by Donepezil, Sleep, and Sleep Deprivation.
Wirsich J, Rey M, Guye M, Bénar C, Lanteaume L, Ridley B, Confort-Gouny S, Cassé-Perrot C, Soulier E, Viout P, Rouby F, Lefebvre MN, Audebert C, Truillet R, Jouve E, Payoux P, Bartrés-Faz D, Bordet R, Richardson JC, Babiloni C, Rossini PM, Micallef J, Blin O, Ranjeva JP; Pharmacog Consortium. Wirsich J, et al. Among authors: lefebvre mn. Brain Topogr. 2018 May;31(3):380-391. doi: 10.1007/s10548-017-0608-5. Epub 2017 Nov 23. Brain Topogr. 2018. PMID: 29170853
Effect of ascorbic acid in patients with Charcot-Marie-Tooth disease type 1A: a multicentre, randomised, double-blind, placebo-controlled trial.
Micallef J, Attarian S, Dubourg O, Gonnaud PM, Hogrel JY, Stojkovic T, Bernard R, Jouve E, Pitel S, Vacherot F, Remec JF, Jomir L, Azabou E, Al-Moussawi M, Lefebvre MN, Attolini L, Yaici S, Tanesse D, Fontes M, Pouget J, Blin O. Micallef J, et al. Among authors: lefebvre mn. Lancet Neurol. 2009 Dec;8(12):1103-10. doi: 10.1016/S1474-4422(09)70260-1. Epub 2009 Oct 7. Lancet Neurol. 2009. PMID: 19818690 Clinical Trial.
Orphan drug clinical development.
Blin O, Lefebvre MN, Rascol O, Micallef J. Blin O, et al. Among authors: lefebvre mn. Therapie. 2020 Apr;75(2):141-147. doi: 10.1016/j.therap.2020.02.004. Epub 2020 Feb 13. Therapie. 2020. PMID: 32247678 Review.
Erratum to: An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A.
Attarian S, Vallat JM, Magy L, Funalot B, Gonnaud PM, Lacour A, Péréon Y, Dubourg O, Pouget J, Micallef J, Franques J, Lefebvre MN, Ghorab K, Al-Moussawi M, Tiffreau V, Preudhomme M, Magot A, Leclair-Visonneau L, Stojkovic T, Bossi L, Lehert P, Gilbert W, Bertrand V, Mandel J, Milet A, Hajj R, Boudiaf L, Scart-Grès C, Nabirotchkin S, Guedj M, Chumakov I, Cohen D. Attarian S, et al. Among authors: lefebvre mn. Orphanet J Rare Dis. 2016 Jul 7;11(1):92. doi: 10.1186/s13023-016-0463-6. Orphanet J Rare Dis. 2016. PMID: 27387831 Free PMC article. No abstract available.
An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A.
Attarian S, Vallat JM, Magy L, Funalot B, Gonnaud PM, Lacour A, Péréon Y, Dubourg O, Pouget J, Micallef J, Franques J, Lefebvre MN, Ghorab K, Al-Moussawi M, Tiffreau V, Preudhomme M, Magot A, Leclair-Visonneau L, Stojkovic T, Bossi L, Lehert P, Gilbert W, Bertrand V, Mandel J, Milet A, Hajj R, Boudiaf L, Scart-Grès C, Nabirotchkin S, Guedj M, Chumakov I, Cohen D. Attarian S, et al. Among authors: lefebvre mn. Orphanet J Rare Dis. 2014 Dec 18;9:199. doi: 10.1186/s13023-014-0199-0. Orphanet J Rare Dis. 2014. PMID: 25519680 Free PMC article. Clinical Trial.
Amygdala activity correlates with attentional bias in PTSD.
El Khoury-Malhame M, Reynaud E, Soriano A, Michael K, Salgado-Pineda P, Zendjidjian X, Gellato C, Eric F, Lefebvre MN, Rouby F, Samuelian JC, Anton JL, Blin O, Khalfa S. El Khoury-Malhame M, et al. Among authors: lefebvre mn. Neuropsychologia. 2011 Jun;49(7):1969-73. doi: 10.1016/j.neuropsychologia.2011.03.025. Epub 2011 Apr 1. Neuropsychologia. 2011. PMID: 21440563
33 results