Jhala US - Search Results

1

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.

Vinckier NK, Patel NA, Geusz RJ, Wang A, Wang J, Matta I, Harrington AR, Wortham M, Wetton N, Wang J, Jhala US, Rosenfeld MG, Benner CW, Shih HP, Sander M. Vinckier NK, et al. Among authors: jhala us. Nat Commun. 2020 Apr 29;11(1):2082. doi: 10.1038/s41467-020-16017-x. Nat Commun. 2020. PMID: 32350257 Free PMC article.

2

Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1.

Sharma S, Jhala US, Johnson T, Ferreri K, Leonard J, Montminy M. Sharma S, et al. Among authors: jhala us. Mol Cell Biol. 1997 May;17(5):2598-604. doi: 10.1128/MCB.17.5.2598. Mol Cell Biol. 1997. PMID: 9111329 Free PMC article.

3

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1.

Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. Herzig S, et al. Among authors: jhala us. Nature. 2001 Sep 13;413(6852):179-83. doi: 10.1038/35093131. Nature. 2001. PMID: 11557984

4

Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic β cell death.

Humphrey RK, Yu SM, Bellary A, Gonuguntla S, Yebra M, Jhala US. Humphrey RK, et al. Among authors: jhala us. J Biol Chem. 2013 Jan 25;288(4):2428-40. doi: 10.1074/jbc.M112.425884. Epub 2012 Nov 21. J Biol Chem. 2013. PMID: 23172226 Free PMC article.

5

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M. Jhala US, et al. Genes Dev. 2003 Jul 1;17(13):1575-80. doi: 10.1101/gad.1097103. Genes Dev. 2003. PMID: 12842910 Free PMC article.

6

Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb.

Lancman JJ, Zvenigorodsky N, Gates KP, Zhang D, Solomon K, Humphrey RK, Kuo T, Setiawan L, Verkade H, Chi YI, Jhala US, Wright CV, Stainier DY, Dong PD. Lancman JJ, et al. Among authors: jhala us. Development. 2013 Jul;140(13):2669-79. doi: 10.1242/dev.090993. Epub 2013 May 29. Development. 2013. PMID: 23720049 Free PMC article.

7

Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus.

Malecki MT, Jhala US, Antonellis A, Fields L, Doria A, Orban T, Saad M, Warram JH, Montminy M, Krolewski AS. Malecki MT, et al. Among authors: jhala us. Nat Genet. 1999 Nov;23(3):323-8. doi: 10.1038/15500. Nat Genet. 1999. PMID: 10545951

8

Loss of TRB3 alters dynamics of MLK3-JNK signaling and inhibits cytokine-activated pancreatic beta cell death.

Humphrey RK, Ray A, Gonuguntla S, Hao E, Jhala US. Humphrey RK, et al. Among authors: jhala us. J Biol Chem. 2014 Oct 24;289(43):29994-30004. doi: 10.1074/jbc.M114.575613. Epub 2014 Sep 9. J Biol Chem. 2014. PMID: 25204656 Free PMC article.

9

Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinases.

Humphrey RK, Yu SM, Flores LE, Jhala US. Humphrey RK, et al. Among authors: jhala us. J Biol Chem. 2010 Jan 29;285(5):3406-16. doi: 10.1074/jbc.M109.006734. Epub 2009 Oct 15. J Biol Chem. 2010. PMID: 19833727 Free PMC article.

10

Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells.

Humphrey RK, Newcomb CJ, Yu SM, Hao E, Yu D, Krajewski S, Du K, Jhala US. Humphrey RK, et al. Among authors: jhala us. J Biol Chem. 2010 Jul 16;285(29):22426-36. doi: 10.1074/jbc.M110.123786. Epub 2010 Apr 26. J Biol Chem. 2010. PMID: 20421299 Free PMC article.

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