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MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial.
Sarker D, Plummer R, Meyer T, Sodergren MH, Basu B, Chee CE, Huang KW, Palmer DH, Ma YT, Evans TRJ, Spalding DRC, Pai M, Sharma R, Pinato DJ, Spicer J, Hunter S, Kwatra V, Nicholls JP, Collin D, Nutbrown R, Glenny H, Fairbairn S, Reebye V, Voutila J, Dorman S, Andrikakou P, Lloyd P, Felstead S, Vasara J, Habib R, Wood C, Saetrom P, Huber HE, Blakey DC, Rossi JJ, Habib N. Sarker D, et al. Among authors: nicholls jp. Clin Cancer Res. 2020 Aug 1;26(15):3936-3946. doi: 10.1158/1078-0432.CCR-20-0414. Epub 2020 May 1. Clin Cancer Res. 2020. PMID: 32357963 Free article. Clinical Trial.
Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo.
Reebye V, Sætrom P, Mintz PJ, Huang KW, Swiderski P, Peng L, Liu C, Liu X, Lindkaer-Jensen S, Zacharoulis D, Kostomitsopoulos N, Kasahara N, Nicholls JP, Jiao LR, Pai M, Spalding DR, Mizandari M, Chikovani T, Emara MM, Haoudi A, Tomalia DA, Rossi JJ, Habib NA. Reebye V, et al. Among authors: nicholls jp. Hepatology. 2014 Jan;59(1):216-27. doi: 10.1002/hep.26669. Epub 2013 Dec 9. Hepatology. 2014. PMID: 23929703 Free PMC article.
Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile.
Huang KW, Reebye V, Czysz K, Ciriello S, Dorman S, Reccia I, Lai HS, Peng L, Kostomitsopoulos N, Nicholls J, Habib RS, Tomalia DA, Sætrom P, Wilkes E, Cutillas P, Rossi JJ, Habib NA. Huang KW, et al. Mol Ther Nucleic Acids. 2020 Mar 6;19:361-370. doi: 10.1016/j.omtn.2019.10.044. Epub 2019 Nov 21. Mol Ther Nucleic Acids. 2020. PMID: 31877412 Free PMC article.
Repeat hepatic resection using a radiofrequency-assisted technique.
El-Gendi AM, Khorsandi SE, Pai M, Zacharoulis D, Nicholls JP, Spalding DR, Jiao LR, Habib NA. El-Gendi AM, et al. Among authors: nicholls jp. Dig Surg. 2008;25(4):293-9. doi: 10.1159/000152845. Epub 2008 Sep 4. Dig Surg. 2008. PMID: 18769067
A multicenter Phase I gene therapy clinical trial involving intraperitoneal administration of E1A-lipid complex in patients with recurrent epithelial ovarian cancer overexpressing HER-2/neu oncogene.
Madhusudan S, Tamir A, Bates N, Flanagan E, Gore ME, Barton DP, Harper P, Seckl M, Thomas H, Lemoine NR, Charnock M, Habib NA, Lechler R, Nicholls J, Pignatelli M, Ganesan TS. Madhusudan S, et al. Clin Cancer Res. 2004 May 1;10(9):2986-96. doi: 10.1158/1078-0432.ccr-03-0291. Clin Cancer Res. 2004. PMID: 15131034 Clinical Trial.
How we do a bloodless partial splenectomy.
Habib NA, Spalding D, Navarra G, Nicholls J. Habib NA, et al. Am J Surg. 2003 Aug;186(2):164-6. doi: 10.1016/s0002-9610(03)00170-3. Am J Surg. 2003. PMID: 12885611
Exploiting human CD34+ stem cell-conditioned medium for tissue repair.
Mintz PJ, Huang KW, Reebye V, Nteliopoulos G, Lai HS, Sætrom P, Kasahara N, Jensen S, Pai M, Gordon MY, Marley SB, Behan R, Spalding DR, Haoudi A, Emara MM, Nicholls J, Rossi JJ, Habib NA. Mintz PJ, et al. Mol Ther. 2014 Jan;22(1):149-59. doi: 10.1038/mt.2013.194. Epub 2013 Aug 28. Mol Ther. 2014. PMID: 23985698 Free PMC article.
39 results