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TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome.
Olsen RHJ, DiBerto JF, English JG, Glaudin AM, Krumm BE, Slocum ST, Che T, Gavin AC, McCorvy JD, Roth BL, Strachan RT. Olsen RHJ, et al. Among authors: roth bl. Nat Chem Biol. 2020 Aug;16(8):841-849. doi: 10.1038/s41589-020-0535-8. Epub 2020 May 4. Nat Chem Biol. 2020. PMID: 32367019 Free PMC article.
Engineering GPCR signaling pathways with RASSLs.
Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL. Conklin BR, et al. Among authors: roth bl. Nat Methods. 2008 Aug;5(8):673-8. doi: 10.1038/nmeth.1232. Nat Methods. 2008. PMID: 18668035 Free PMC article. Review.
Engineered GPCRs as tools to modulate signal transduction.
Pei Y, Rogan SC, Yan F, Roth BL. Pei Y, et al. Among authors: roth bl. Physiology (Bethesda). 2008 Dec;23:313-21. doi: 10.1152/physiol.00025.2008. Physiology (Bethesda). 2008. PMID: 19074739 Free article. Review.
Structural features for functional selectivity at serotonin receptors.
Wacker D, Wang C, Katritch V, Han GW, Huang XP, Vardy E, McCorvy JD, Jiang Y, Chu M, Siu FY, Liu W, Xu HE, Cherezov V, Roth BL, Stevens RC. Wacker D, et al. Among authors: roth bl. Science. 2013 May 3;340(6132):615-9. doi: 10.1126/science.1232808. Epub 2013 Mar 21. Science. 2013. PMID: 23519215 Free PMC article.
538 results