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934 results

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PTPσ inhibitors promote hematopoietic stem cell regeneration.
Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP. Zhang Y, et al. Among authors: roos m. Nat Commun. 2019 Aug 14;10(1):3667. doi: 10.1038/s41467-019-11490-5. Nat Commun. 2019. PMID: 31413255 Free PMC article.
Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution.
Termini CM, Pang A, Fang T, Roos M, Chang VY, Zhang Y, Setiawan NJ, Signaevskaia L, Li M, Kim MM, Tabibi O, Lin PK, Sasine JP, Chatterjee A, Murali R, Himburg HA, Chute JP. Termini CM, et al. Among authors: roos m. Nat Commun. 2021 Nov 30;12(1):6990. doi: 10.1038/s41467-021-27263-y. Nat Commun. 2021. PMID: 34848712 Free PMC article.
Wild-type Kras expands and exhausts hematopoietic stem cells.
Sasine JP, Himburg HA, Termini CM, Roos M, Tran E, Zhao L, Kan J, Li M, Zhang Y, de Barros SC, Rao DS, Counter CM, Chute JP. Sasine JP, et al. Among authors: roos m. JCI Insight. 2018 Jun 7;3(11):e98197. doi: 10.1172/jci.insight.98197. eCollection 2018 Jun 7. JCI Insight. 2018. PMID: 29875320 Free PMC article.
Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling.
Himburg HA, Roos M, Fang T, Zhang Y, Termini CM, Schlussel L, Kim M, Pang A, Kan J, Zhao L, Suh H, Sasine JP, Sapparapu G, Bowers PM, Schiller G, Chute JP. Himburg HA, et al. Among authors: roos m. J Clin Invest. 2020 Jan 2;130(1):315-328. doi: 10.1172/JCI129061. J Clin Invest. 2020. PMID: 31613796 Free PMC article.
A small molecule screen to identify regulators of let-7 targets.
Cinkornpumin J, Roos M, Nguyen L, Liu X, Gaeta X, Lin S, Chan DN, Liu A, Gregory RI, Jung M, Chute J, Zhu H, Lowry WE. Cinkornpumin J, et al. Among authors: roos m. Sci Rep. 2017 Nov 21;7(1):15973. doi: 10.1038/s41598-017-16258-9. Sci Rep. 2017. PMID: 29162914 Free PMC article.
A Small-Molecule Inhibitor of Lin28.
Roos M, Pradère U, Ngondo RP, Behera A, Allegrini S, Civenni G, Zagalak JA, Marchand JR, Menzi M, Towbin H, Scheuermann J, Neri D, Caflisch A, Catapano CV, Ciaudo C, Hall J. Roos M, et al. ACS Chem Biol. 2016 Oct 21;11(10):2773-2781. doi: 10.1021/acschembio.6b00232. Epub 2016 Aug 22. ACS Chem Biol. 2016. PMID: 27548809
934 results