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Toward the Design of Less Hazardous Chemicals: Exploring Comparative Oxidative Stress in Two Common Animal Models.
Corrales J, Kristofco LA, Steele WB, Saari GN, Kostal J, Williams ES, Mills M, Gallagher EP, Kavanagh TJ, Simcox N, Shen LQ, Melnikov F, Zimmerman JB, Voutchkova-Kostal AM, Anastas PT, Brooks BW. Corrales J, et al. Among authors: anastas pt. Chem Res Toxicol. 2017 Apr 17;30(4):893-904. doi: 10.1021/acs.chemrestox.6b00246. Epub 2016 Nov 3. Chem Res Toxicol. 2017. PMID: 27750016
The Molecular Design Research Network.
Coish P, Brooks BW, Gallagher EP, Mills M, Kavanagh TJ, Simcox N, Lasker GA, Botta D, Schmuck SC, Voutchkova-Kostal A, Kostal J, Mullins ML, Nesmith SM, Mellor KE, Corrales J, Kristofco LA, Saari GN, Steele B, Shen LQ, Melnikov F, Zimmerman JB, Anastas PT. Coish P, et al. Among authors: anastas pt. Toxicol Sci. 2018 Feb 1;161(2):241-248. doi: 10.1093/toxsci/kfx175. Toxicol Sci. 2018. PMID: 28973416 Review.
Kinetics of Glutathione Depletion and Antioxidant Gene Expression as Indicators of Chemical Modes of Action Assessed in Vitro in Mouse Hepatocytes with Enhanced Glutathione Synthesis.
Melnikov F, Botta D, White CC, Schmuck SC, Winfough M, Schaupp CM, Gallagher EP, Brooks BW, Williams ES, Coish P, Anastas PT, Voutchkova-Kostal A, Kostal J, Kavanagh TJ. Melnikov F, et al. Among authors: anastas pt. Chem Res Toxicol. 2019 Mar 18;32(3):421-436. doi: 10.1021/acs.chemrestox.8b00259. Epub 2019 Jan 7. Chem Res Toxicol. 2019. PMID: 30547568 Free PMC article.
Toward Less Hazardous Industrial Compounds: Coupling Quantum Mechanical Computations, Biomarker Responses, and Behavioral Profiles To Identify Bioactivity of SN2 Electrophiles in Alternative Vertebrate Models.
Steele WB, Kristofco LA, Corrales J, Saari GN, Corcoran EJ, Hill BN, Mills MG, Gallagher E, Kavanagh TJ, Melnikov F, Zimmerman JB, Voutchkova-Kostal A, Anastas PT, Kostal J, Brooks BW. Steele WB, et al. Among authors: anastas pt. Chem Res Toxicol. 2020 Feb 17;33(2):367-380. doi: 10.1021/acs.chemrestox.9b00290. Epub 2019 Dec 16. Chem Res Toxicol. 2020. PMID: 31789507
CRISPR-Generated Nrf2a Loss- and Gain-of-Function Mutants Facilitate Mechanistic Analysis of Chemical Oxidative Stress-Mediated Toxicity in Zebrafish.
Mills MG, Ramsden R, Ma EY, Corrales J, Kristofco LA, Steele WB, Saari GN, Melnikov F, Kostal J, Kavanagh TJ, Zimmerman JB, Voutchkova-Kostal AM, Brooks BW, Coish P, Anastas PT, Gallagher E. Mills MG, et al. Among authors: anastas pt. Chem Res Toxicol. 2020 Feb 17;33(2):426-435. doi: 10.1021/acs.chemrestox.9b00346. Epub 2020 Jan 8. Chem Res Toxicol. 2020. PMID: 31858786 Free PMC article.
Identifying and designing chemicals with minimal acute aquatic toxicity.
Kostal J, Voutchkova-Kostal A, Anastas PT, Zimmerman JB. Kostal J, et al. Among authors: anastas pt. Proc Natl Acad Sci U S A. 2015 May 19;112(20):6289-94. doi: 10.1073/pnas.1314991111. Epub 2014 Mar 17. Proc Natl Acad Sci U S A. 2015. PMID: 24639521 Free PMC article.
Advancing the next generation of health risk assessment.
Cote I, Anastas PT, Birnbaum LS, Clark RM, Dix DJ, Edwards SW, Preuss PW. Cote I, et al. Among authors: anastas pt. Environ Health Perspect. 2012 Nov;120(11):1499-502. doi: 10.1289/ehp.1104870. Epub 2012 Aug 8. Environ Health Perspect. 2012. PMID: 22875311 Free PMC article.
73 results