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Page 1
Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets.
Psaila B, Wang G, Rodriguez-Meira A, Li R, Heuston EF, Murphy L, Yee D, Hitchcock IS, Sousos N, O'Sullivan J, Anderson S, Senis YA, Weinberg OK, Calicchio ML; NIH Intramural Sequencing Center; Iskander D, Royston D, Milojkovic D, Roberts I, Bodine DM, Thongjuea S, Mead AJ. Psaila B, et al. Among authors: heuston ef. Mol Cell. 2020 May 7;78(3):477-492.e8. doi: 10.1016/j.molcel.2020.04.008. Mol Cell. 2020. PMID: 32386542 Free PMC article.
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development.
Roy A, Wang G, Iskander D, O'Byrne S, Elliott N, O'Sullivan J, Buck G, Heuston EF, Wen WX, Meira AR, Hua P, Karadimitris A, Mead AJ, Bodine DM, Roberts I, Psaila B, Thongjuea S. Roy A, et al. Among authors: heuston ef. Cell Rep. 2021 Sep 14;36(11):109698. doi: 10.1016/j.celrep.2021.109698. Cell Rep. 2021. PMID: 34525349 Free PMC article.
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia.
Iskander D, Wang G, Heuston EF, Christodoulidou C, Psaila B, Ponnusamy K, Ren H, Mokhtari Z, Robinson M, Chaidos A, Trivedi P, Trasanidis N, Katsarou A, Szydlo R, Palii CG, Zaidi MH, Al-Oqaily Q, Caputo VS, Roy A, Harrington Y, Karnik L, Naresh K, Mead AJ, Thongjuea S, Brand M, de la Fuente J, Bodine DM, Roberts I, Karadimitris A. Iskander D, et al. Among authors: heuston ef. Sci Transl Med. 2021 Sep 8;13(610):eabf0113. doi: 10.1126/scitranslmed.abf0113. Epub 2021 Sep 8. Sci Transl Med. 2021. PMID: 34516827
SBR-Blood: systems biology repository for hematopoietic cells.
Lichtenberg J, Heuston EF, Mishra T, Keller CA, Hardison RC, Bodine DM. Lichtenberg J, et al. Among authors: heuston ef. Nucleic Acids Res. 2016 Jan 4;44(D1):D925-31. doi: 10.1093/nar/gkv1263. Epub 2015 Nov 20. Nucleic Acids Res. 2016. PMID: 26590403 Free PMC article.
An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis.
Xiang G, Keller CA, Heuston E, Giardine BM, An L, Wixom AQ, Miller A, Cockburn A, Sauria MEG, Weaver K, Lichtenberg J, Göttgens B, Li Q, Bodine D, Mahony S, Taylor J, Blobel GA, Weiss MJ, Cheng Y, Yue F, Hughes J, Higgs DR, Zhang Y, Hardison RC. Xiang G, et al. Genome Res. 2020 Mar;30(3):472-484. doi: 10.1101/gr.255760.119. Epub 2020 Mar 4. Genome Res. 2020. PMID: 32132109 Free PMC article.
Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells.
Hardison RC, Zhang Y, Keller CA, Xiang G, Heuston EF, An L, Lichtenberg J, Giardine BM, Bodine D, Mahony S, Li Q, Yue F, Weiss MJ, Blobel GA, Taylor J, Hughes J, Higgs DR, Göttgens B. Hardison RC, et al. Among authors: heuston ef. IUBMB Life. 2020 Jan;72(1):27-38. doi: 10.1002/iub.2195. Epub 2019 Nov 25. IUBMB Life. 2020. PMID: 31769130 Free PMC article. Review.
Effects of sheared chromatin length on ChIP-seq quality and sensitivity.
Keller CA, Wixom AQ, Heuston EF, Giardine B, Hsiung CC, Long MR, Miller A, Anderson SM, Cockburn A, Blobel GA, Bodine DM, Hardison RC. Keller CA, et al. Among authors: heuston ef. G3 (Bethesda). 2021 Jun 17;11(6):jkab101. doi: 10.1093/g3journal/jkab101. G3 (Bethesda). 2021. PMID: 33788948 Free PMC article.
"Stripe" transcription factors provide accessibility to co-binding partners in mammalian genomes.
Zhao Y, Vartak SV, Conte A, Wang X, Garcia DA, Stevens E, Kyoung Jung S, Kieffer-Kwon KR, Vian L, Stodola T, Moris F, Chopp L, Preite S, Schwartzberg PL, Kulinski JM, Olivera A, Harly C, Bhandoola A, Heuston EF, Bodine DM, Urrutia R, Upadhyaya A, Weirauch MT, Hager G, Casellas R. Zhao Y, et al. Among authors: heuston ef. Mol Cell. 2022 Sep 15;82(18):3398-3411.e11. doi: 10.1016/j.molcel.2022.06.029. Epub 2022 Jul 20. Mol Cell. 2022. PMID: 35863348 Free PMC article.
21 results