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Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons.
Galan-Acosta L, Sierra C, Leppert A, Pouliopoulos AN, Kwon N, Noel RL, Tambaro S, Presto J, Nilsson P, Konofagou EE, Johansson J. Galan-Acosta L, et al. Among authors: johansson j. Mol Cell Neurosci. 2020 Jun;105:103498. doi: 10.1016/j.mcn.2020.103498. Epub 2020 May 8. Mol Cell Neurosci. 2020. PMID: 32389804 Free article.
High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C.
Willander H, Askarieh G, Landreh M, Westermark P, Nordling K, Keränen H, Hermansson E, Hamvas A, Nogee LM, Bergman T, Saenz A, Casals C, Åqvistg J, Jörnvall H, Berglund H, Presto J, Knight SD, Johansson J. Willander H, et al. Among authors: johansson j. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2325-9. doi: 10.1073/pnas.1114740109. Epub 2012 Feb 2. Proc Natl Acad Sci U S A. 2012. PMID: 22308375 Free PMC article.
BRICHOS domains efficiently delay fibrillation of amyloid β-peptide.
Willander H, Presto J, Askarieh G, Biverstål H, Frohm B, Knight SD, Johansson J, Linse S. Willander H, et al. Among authors: johansson j. J Biol Chem. 2012 Sep 7;287(37):31608-17. doi: 10.1074/jbc.M112.393157. Epub 2012 Jul 16. J Biol Chem. 2012. PMID: 22801430 Free PMC article.
Control of amyloid assembly by autoregulation.
Landreh M, Johansson J, Rising A, Presto J, Jörnvall H. Landreh M, et al. Among authors: johansson j. Biochem J. 2012 Oct 15;447(2):185-92. doi: 10.1042/BJ20120919. Biochem J. 2012. PMID: 23013511 Review.
Amyloid-β-induced action potential desynchronization and degradation of hippocampal gamma oscillations is prevented by interference with peptide conformation change and aggregation.
Kurudenkandy FR, Zilberter M, Biverstål H, Presto J, Honcharenko D, Strömberg R, Johansson J, Winblad B, Fisahn A. Kurudenkandy FR, et al. Among authors: johansson j. J Neurosci. 2014 Aug 20;34(34):11416-25. doi: 10.1523/JNEUROSCI.1195-14.2014. J Neurosci. 2014. PMID: 25143621 Free PMC article.
1,651 results