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Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons.
Galan-Acosta L, Sierra C, Leppert A, Pouliopoulos AN, Kwon N, Noel RL, Tambaro S, Presto J, Nilsson P, Konofagou EE, Johansson J. Galan-Acosta L, et al. Among authors: leppert a. Mol Cell Neurosci. 2020 Jun;105:103498. doi: 10.1016/j.mcn.2020.103498. Epub 2020 May 8. Mol Cell Neurosci. 2020. PMID: 32389804 Free article.
Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state.
Chen G, Abelein A, Nilsson HE, Leppert A, Andrade-Talavera Y, Tambaro S, Hemmingsson L, Roshan F, Landreh M, Biverstål H, Koeck PJB, Presto J, Hebert H, Fisahn A, Johansson J. Chen G, et al. Among authors: leppert a. Nat Commun. 2017 Dec 12;8(1):2081. doi: 10.1038/s41467-017-02056-4. Nat Commun. 2017. PMID: 29234026 Free PMC article.
34 results