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Recombinant BRICHOS chaperone domains delivered to mouse brain parenchyma by focused ultrasound and microbubbles are internalized by hippocampal and cortical neurons.
Mol Cell Neurosci. 2020 Jun;105:103498. doi: 10.1016/j.mcn.2020.103498. Epub 2020 May 8.
Mol Cell Neurosci. 2020.
PMID: 32389804
Free article.
Transcranial Theranostic Ultrasound for Pre-Planning and Blood-Brain Barrier Opening: A Feasibility Study Using an Imaging Phased Array In Vitro and In Vivo.
Batts A, Ji R, Kline-Schoder A, Noel R, Konofagou E.
Batts A, et al.
IEEE Trans Biomed Eng. 2022 Apr;69(4):1481-1490. doi: 10.1109/TBME.2021.3120919. Epub 2022 Mar 18.
IEEE Trans Biomed Eng. 2022.
PMID: 34665716
Free PMC article.
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Non-invasive optogenetics with ultrasound-mediated gene delivery and red-light excitation.
Pouliopoulos AN, Murillo MF, Noel RL, Batts AJ, Ji R, Kwon N, Yu H, Tong CK, Gelinas JN, Araghy DK, Hussaini SA, Konofagou EE.
Pouliopoulos AN, et al. Among authors: noel rl.
Brain Stimul. 2022 Jul-Aug;15(4):927-941. doi: 10.1016/j.brs.2022.06.007. Epub 2022 Jun 16.
Brain Stimul. 2022.
PMID: 35718324
Free PMC article.
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Using a novel rapid alternating steering angles pulse sequence to evaluate the impact of theranostic ultrasound-mediated ultra-short pulse length on blood-brain barrier opening volume and closure, cavitation mapping, drug delivery feasibility, and safety.
Batts AJ, Ji R, Noel RL, Kline-Schoder AR, Bae S, Kwon N, Konofagou EE.
Batts AJ, et al. Among authors: noel rl.
Theranostics. 2023 Feb 5;13(3):1180-1197. doi: 10.7150/thno.76199. eCollection 2023.
Theranostics. 2023.
PMID: 36793858
Free PMC article.
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Natural aging and Alzheimer's disease pathology increase susceptibility to focused ultrasound-induced blood-brain barrier opening.
Noel RL, Batts AJ, Ji R, Pouliopoulos AN, Bae S, Kline-Schoder AR, Konofagou EE.
Noel RL, et al.
Sci Rep. 2023 Apr 25;13(1):6757. doi: 10.1038/s41598-023-30466-6.
Sci Rep. 2023.
PMID: 37185578
Free PMC article.
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Getting ahead of Alzheimer's disease: early intervention with focused ultrasound.
Noel RL, Gorman SL, Batts AJ, Konofagou EE.
Noel RL, et al.
Front Neurosci. 2023 Jul 27;17:1229683. doi: 10.3389/fnins.2023.1229683. eCollection 2023.
Front Neurosci. 2023.
PMID: 37575309
Free PMC article.
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Characterization of the responses of brain macrophages to focused ultrasound-mediated blood-brain barrier opening.
Kline-Schoder AR, Chintamen S, Willner MJ, DiBenedetto MR, Noel RL, Batts AJ, Kwon N, Zacharoulis S, Wu CC, Menon V, Kernie SG, Konofagou EE.
Kline-Schoder AR, et al. Among authors: noel rl.
Nat Biomed Eng. 2023 Oct 19. doi: 10.1038/s41551-023-01107-0. Online ahead of print.
Nat Biomed Eng. 2023.
PMID: 37857722
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