Downes DP - Search Results

1

Impact of Extracellular Fatty Acids and Oxygen Tension on Lipid Synthesis and Assembly in Pancreatic Cancer Cells.

Downes DP, Daurio NA, McLaren DG, Carrington P, Previs SF, Williams KB. Downes DP, et al. ACS Chem Biol. 2020 Jul 17;15(7):1892-1900. doi: 10.1021/acschembio.0c00219. Epub 2020 May 26. ACS Chem Biol. 2020. PMID: 32396332

2

Key Concepts Surrounding Studies of Stable Isotope-Resolved Metabolomics.

Previs SF, Downes DP. Previs SF, et al. Among authors: downes dp. Methods Mol Biol. 2020;2104:99-120. doi: 10.1007/978-1-0716-0239-3_6. Methods Mol Biol. 2020. PMID: 31953814

3

Mapping Lipogenic Flux: A Gold LDI-MS Approach for Imaging Neutral Lipid Kinetics.

Downes DP, Zhong W, Zhang J, Chen B, Satapati S, Metzger D, Godinez G, Lao J, Sheth PR, McLaren DG, Talukdar S, Previs SF. Downes DP, et al. J Am Soc Mass Spectrom. 2020 Dec 2;31(12):2421-2425. doi: 10.1021/jasms.0c00199. Epub 2020 Sep 1. J Am Soc Mass Spectrom. 2020. PMID: 32840373

4

Isotope Fractionation during Gas Chromatography Can Enhance Mass Spectrometry-Based Measures of ²H-Labeling of Small Molecules.

Downes DP, Kasumov T, Daurio NA, Wood NB, Previs MJ, Sheth PR, McLaren DG, Previs SF. Downes DP, et al. Metabolites. 2020 Nov 20;10(11):474. doi: 10.3390/metabo10110474. Metabolites. 2020. PMID: 33233825 Free PMC article.

5

Using measures of metabolic flux to align screening and clinical development: Avoiding pitfalls to enable translational studies.

Satapati S, Downes DP, Metzger D, Shankaran H, Talukdar S, Zhou Y, Ren Z, Chen M, Lim YH, Hatcher NG, Wen X, Sheth PR, McLaren DG, Previs SF. Satapati S, et al. Among authors: downes dp. SLAS Discov. 2022 Jan;27(1):20-28. doi: 10.1016/j.slasd.2021.10.015. Epub 2021 Nov 2. SLAS Discov. 2022. PMID: 35058172 Free article.

6

Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states.

Daurio NA, Wang Y, Chen Y, Zhou H, Carballo-Jane E, Mane J, Rodriguez CG, Zafian P, Houghton A, Addona G, McLaren DG, Zhang R, Shyong BJ, Bateman K, Downes DP, Webb M, Kelley DE, Previs SF. Daurio NA, et al. Among authors: downes dp. Am J Physiol Endocrinol Metab. 2019 Jun 1;316(6):E1105-E1117. doi: 10.1152/ajpendo.00459.2018. Epub 2019 Mar 26. Am J Physiol Endocrinol Metab. 2019. PMID: 30912961 Free article.

7

Engineering the Next Generation of Matched Models for Chemical Translational Biology.

Downes DP. Downes DP. Chembiochem. 2021 Feb 15;22(4):642. doi: 10.1002/cbic.202000520. Epub 2020 Nov 13. Chembiochem. 2021. PMID: 33184916

8

Characterization of Brain Metabolism by Nuclear Magnetic Resonance.

Downes DP, Collins JHP, Lama B, Zeng H, Nguyen T, Keller G, Febo M, Long JR. Downes DP, et al. Chemphyschem. 2019 Jan 21;20(2):216-230. doi: 10.1002/cphc.201800917. Epub 2018 Dec 20. Chemphyschem. 2019. PMID: 30536696 Free PMC article. Review.

9

Stromal cell-derived factor-1 promoted angiogenesis and inflammatory cell infiltration in aneurysm walls.

Hoh BL, Hosaka K, Downes DP, Nowicki KW, Wilmer EN, Velat GJ, Scott EW. Hoh BL, et al. Among authors: downes dp. J Neurosurg. 2014 Jan;120(1):73-86. doi: 10.3171/2013.9.JNS122074. Epub 2013 Oct 25. J Neurosurg. 2014. PMID: 24160472 Free PMC article.

10

Modified murine intracranial aneurysm model: aneurysm formation and rupture by elastase and hypertension.

Hosaka K, Downes DP, Nowicki KW, Hoh BL. Hosaka K, et al. Among authors: downes dp. J Neurointerv Surg. 2014 Jul;6(6):474-9. doi: 10.1136/neurintsurg-2013-010788. Epub 2013 Aug 13. J Neurointerv Surg. 2014. PMID: 23943816 Free PMC article.

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