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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor.
Martin LJ, Koegl M, Bader G, Cockcroft XL, Fedorov O, Fiegen D, Gerstberger T, Hofmann MH, Hohmann AF, Kessler D, Knapp S, Knesl P, Kornigg S, Müller S, Nar H, Rogers C, Rumpel K, Schaaf O, Steurer S, Tallant C, Vakoc CR, Zeeb M, Zoephel A, Pearson M, Boehmelt G, McConnell D. Martin LJ, et al. Among authors: fiegen d. J Med Chem. 2016 May 26;59(10):4462-75. doi: 10.1021/acs.jmedchem.5b01865. Epub 2016 Mar 10. J Med Chem. 2016. PMID: 26914985 Free PMC article.
Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule.
Tautermann CS, Binder F, Büttner FH, Eickmeier C, Fiegen D, Gross U, Grundl MA, Heilker R, Hobson S, Hoerer S, Luippold A, Mack V, Montel F, Peters S, Bhattacharya S, Vaidehi N, Schnapp G, Thamm S, Zeeb M. Tautermann CS, et al. Among authors: fiegen d. J Med Chem. 2019 Jan 10;62(1):306-316. doi: 10.1021/acs.jmedchem.8b00857. Epub 2018 Sep 12. J Med Chem. 2019. PMID: 30207464
MALDI-TOF-Based Affinity Selection Mass Spectrometry for Automated Screening of Protein-Ligand Interactions at High Throughput.
Simon RP, Winter M, Kleiner C, Wehrle L, Karnath M, Ries R, Zeeb M, Schnapp G, Fiegen D, Häbe TT, Runge F, Bretschneider T, Luippold AH, Bischoff D, Reindl W, Büttner FH. Simon RP, et al. Among authors: fiegen d. SLAS Discov. 2021 Jan;26(1):44-57. doi: 10.1177/2472555220959266. Epub 2020 Oct 17. SLAS Discov. 2021. PMID: 33073664 Free article.
Crystal structure of Rnd3/RhoE: functional implications.
Fiegen D, Blumenstein L, Stege P, Vetter IR, Ahmadian MR. Fiegen D, et al. FEBS Lett. 2002 Aug 14;525(1-3):100-4. doi: 10.1016/s0014-5793(02)03094-6. FEBS Lett. 2002. PMID: 12163169 Free article.
13 results