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MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer.
Cipponi A, Goode DL, Bedo J, McCabe MJ, Pajic M, Croucher DR, Rajal AG, Junankar SR, Saunders DN, Lobachevsky P, Papenfuss AT, Nessem D, Nobis M, Warren SC, Timpson P, Cowley M, Vargas AC, Qiu MR, Generali DG, Keerthikumar S, Nguyen U, Corcoran NM, Long GV, Blay JY, Thomas DM. Cipponi A, et al. Among authors: vargas ac. Science. 2020 Jun 5;368(6495):1127-1131. doi: 10.1126/science.aau8768. Science. 2020. PMID: 32499442
FISH analysis of selected soft tissue tumors: Diagnostic experience in a tertiary center.
Vargas AC, Selinger C, Satgunaseelan L, Cooper WA, Gupta R, Stalley P, Brown W, Soper J, Schatz J, Boyle R, Thomas DM, Tattersall MHN, Bhadri V, Maclean F, Bonar SF, Scolyer RA, Karim RZ, McCarthy SW, Mahar A, O'Toole SA. Vargas AC, et al. Asia Pac J Clin Oncol. 2019 Feb;15(1):38-47. doi: 10.1111/ajco.12980. Epub 2018 May 28. Asia Pac J Clin Oncol. 2019. PMID: 29806089
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.
Coulson R, Liew SH, Connelly AA, Yee NS, Deb S, Kumar B, Vargas AC, O'Toole SA, Parslow AC, Poh A, Putoczki T, Morrow RJ, Alorro M, Lazarus KA, Yeap EFW, Walton KL, Harrison CA, Hannan NJ, George AJ, Clyne CD, Ernst M, Allen AM, Chand AL. Coulson R, et al. Among authors: vargas ac. Oncotarget. 2017 Mar 21;8(12):18640-18656. doi: 10.18632/oncotarget.15553. Oncotarget. 2017. PMID: 28416734 Free PMC article.
RacGAP1 Is a Novel Downstream Effector of E2F7-Dependent Resistance to Doxorubicin and Is Prognostic for Overall Survival in Squamous Cell Carcinoma.
Hazar-Rethinam M, de Long LM, Gannon OM, Boros S, Vargas AC, Dzienis M, Mukhopadhyay P, Saenz-Ponce N, Dantzic DD, Simpson F, Saunders NA. Hazar-Rethinam M, et al. Among authors: vargas ac. Mol Cancer Ther. 2015 Aug;14(8):1939-50. doi: 10.1158/1535-7163.MCT-15-0076. Epub 2015 May 27. Mol Cancer Ther. 2015. PMID: 26018753
When used together SS18-SSX fusion-specific and SSX C-terminus immunohistochemistry are highly specific and sensitive for the diagnosis of synovial sarcoma and can replace FISH or molecular testing in most cases.
Zaborowski M, Vargas AC, Pulvers J, Clarkson A, de Guzman D, Sioson L, Maclean F, Chou A, Gill AJ. Zaborowski M, et al. Among authors: vargas ac. Histopathology. 2020 Oct;77(4):588-600. doi: 10.1111/his.14190. Epub 2020 Sep 12. Histopathology. 2020. PMID: 32559341
Phenotype-genotype correlation in familial breast cancer.
Vargas AC, Reis-Filho JS, Lakhani SR. Vargas AC, et al. J Mammary Gland Biol Neoplasia. 2011 Apr;16(1):27-40. doi: 10.1007/s10911-011-9204-6. Epub 2011 Mar 12. J Mammary Gland Biol Neoplasia. 2011. PMID: 21400086 Review.
Multidimensional phenotyping of breast cancer cell lines to guide preclinical research.
Saunus JM, Smart CE, Kutasovic JR, Johnston RL, Kalita-de Croft P, Miranda M, Rozali EN, Vargas AC, Reid LE, Lorsy E, Cocciardi S, Seidens T, McCart Reed AE, Dalley AJ, Wockner LF, Johnson J, Sarkar D, Askarian-Amiri ME, Simpson PT, Khanna KK, Chenevix-Trench G, Al-Ejeh F, Lakhani SR. Saunus JM, et al. Among authors: vargas ac. Breast Cancer Res Treat. 2018 Jan;167(1):289-301. doi: 10.1007/s10549-017-4496-x. Epub 2017 Sep 9. Breast Cancer Res Treat. 2018. PMID: 28889351
114 results