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Multicentric, prospective observational data show sperm capacitation predicts male fertility, and cohort comparison reveals a high prevalence of impaired capacitation in men questioning their fertility.
Sharara F, Seaman E, Morris R, Schinfeld J, Nichols J, Sobel M, Lee A, Somkuti S, Hirshberg S, Budinetz T, Barmat L, Palermo G, Rosenwaks Z, Bar-Chama N, Bodie J, Nichols J, Payne J, McCoy T, Tarnawa E, Whitman-Elia G, Weissmann L, Doukakis M, Hurwitz J, Leondires M, Murdock C, Ressler I, Richlin S, Williams S, Wosnitzer M, Butcher M, Kashanian J, Ahlering P, Aubuchon M, Ostermeier GC, Travis AJ. Sharara F, et al. Among authors: tarnawa e. Reprod Biomed Online. 2020 Jul;41(1):69-79. doi: 10.1016/j.rbmo.2020.03.011. Epub 2020 May 1. Reprod Biomed Online. 2020. PMID: 32505543 Free article.
PAX7 expression defines germline stem cells in the adult testis.
Aloisio GM, Nakada Y, Saatcioglu HD, Peña CG, Baker MD, Tarnawa ED, Mukherjee J, Manjunath H, Bugde A, Sengupta AL, Amatruda JF, Cuevas I, Hamra FK, Castrillon DH. Aloisio GM, et al. Among authors: tarnawa ed. J Clin Invest. 2014 Sep;124(9):3929-44. doi: 10.1172/JCI75943. Epub 2014 Aug 18. J Clin Invest. 2014. PMID: 25133429 Free PMC article.
The small GTPase Rheb is required for spermatogenesis but not oogenesis.
Baker MD, Ezzati M, Aloisio GM, Tarnawa ED, Cuevas I, Nakada Y, Castrillon DH. Baker MD, et al. Among authors: tarnawa ed. Reproduction. 2014 Apr 8;147(5):615-25. doi: 10.1530/REP-13-0304. Print 2014 May. Reproduction. 2014. PMID: 24713393 Free PMC article.