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The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites.
Charnaud SC, Dixon MWA, Nie CQ, Chappell L, Sanders PR, Nebl T, Hanssen E, Berriman M, Chan JA, Blanch AJ, Beeson JG, Rayner JC, Przyborski JM, Tilley L, Crabb BS, Gilson PR. Charnaud SC, et al. Among authors: chappell l. PLoS One. 2017 Jul 21;12(7):e0181656. doi: 10.1371/journal.pone.0181656. eCollection 2017. PLoS One. 2017. PMID: 28732045 Free PMC article.
RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics.
Claessens A, Harris LM, Stanojcic S, Chappell L, Stanton A, Kuk N, Veneziano-Broccia P, Sterkers Y, Rayner JC, Merrick CJ. Claessens A, et al. Among authors: chappell l. PLoS Genet. 2018 Jul 2;14(7):e1007490. doi: 10.1371/journal.pgen.1007490. eCollection 2018 Jul. PLoS Genet. 2018. PMID: 29965959 Free PMC article.
Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites.
Brochet M, Collins MO, Smith TK, Thompson E, Sebastian S, Volkmann K, Schwach F, Chappell L, Gomes AR, Berriman M, Rayner JC, Baker DA, Choudhary J, Billker O. Brochet M, et al. Among authors: chappell l. PLoS Biol. 2014 Mar 4;12(3):e1001806. doi: 10.1371/journal.pbio.1001806. eCollection 2014 Mar. PLoS Biol. 2014. PMID: 24594931 Free PMC article.
Vector transmission regulates immune control of Plasmodium virulence.
Spence PJ, Jarra W, Lévy P, Reid AJ, Chappell L, Brugat T, Sanders M, Berriman M, Langhorne J. Spence PJ, et al. Among authors: chappell l. Nature. 2013 Jun 13;498(7453):228-31. doi: 10.1038/nature12231. Epub 2013 May 29. Nature. 2013. PMID: 23719378 Free PMC article.
442 results