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Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade.
Wang Y, Nanda V, Direnzo D, Ye J, Xiao S, Kojima Y, Howe KL, Jarr KU, Flores AM, Tsantilas P, Tsao N, Rao A, Newman AAC, Eberhard AV, Priest JR, Ruusalepp A, Pasterkamp G, Maegdefessel L, Miller CL, Lind L, Koplev S, Björkegren JLM, Owens GK, Ingelsson E, Weissman IL, Leeper NJ. Wang Y, et al. Among authors: howe kl. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15818-15826. doi: 10.1073/pnas.2006348117. Epub 2020 Jun 15. Proc Natl Acad Sci U S A. 2020. PMID: 32541024 Free PMC article.
Combined Cardiac Fluorodeoxyglucose-Positron Emission Tomography/Magnetic Resonance Imaging Assessment of Myocardial Injury in Patients Who Recently Recovered From COVID-19.
Hanneman K, Houbois C, Schoffel A, Gustafson D, Iwanochko RM, Wintersperger BJ, Chan R, Fish JE, Howe KL, Thavendiranathan P. Hanneman K, et al. Among authors: howe kl. JAMA Cardiol. 2022 Mar 1;7(3):298-308. doi: 10.1001/jamacardio.2021.5505. JAMA Cardiol. 2022. PMID: 35019953 Free PMC article.
MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes.
Veitch S, Njock MS, Chandy M, Siraj MA, Chi L, Mak H, Yu K, Rathnakumar K, Perez-Romero CA, Chen Z, Alibhai FJ, Gustafson D, Raju S, Wu R, Zarrin Khat D, Wang Y, Caballero A, Meagher P, Lau E, Pepic L, Cheng HS, Galant NJ, Howe KL, Li RK, Connelly KA, Husain M, Delgado-Olguin P, Fish JE. Veitch S, et al. Among authors: howe kl. Cardiovasc Diabetol. 2022 Feb 24;21(1):31. doi: 10.1186/s12933-022-01458-z. Cardiovasc Diabetol. 2022. PMID: 35209901 Free PMC article.
Cardiovascular signatures of COVID-19 predict mortality and identify barrier stabilizing therapies.
Gustafson D, Ngai M, Wu R, Hou H, Schoffel AC, Erice C, Mandla S, Billia F, Wilson MD, Radisic M, Fan E, Trahtemberg U, Baker A, McIntosh C, Fan CS, Dos Santos CC, Kain KC, Hanneman K, Thavendiranathan P, Fish JE, Howe KL. Gustafson D, et al. Among authors: howe kl. EBioMedicine. 2022 Apr;78:103982. doi: 10.1016/j.ebiom.2022.103982. Epub 2022 Apr 8. EBioMedicine. 2022. PMID: 35405523 Free PMC article.
81 results