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FOXO1 promotes HIV latency by suppressing ER stress in T cells.
Vallejo-Gracia A, Chen IP, Perrone R, Besnard E, Boehm D, Battivelli E, Tezil T, Krey K, Raymond KA, Hull PA, Walter M, Habrylo I, Cruz A, Deeks S, Pillai S, Verdin E, Ott M. Vallejo-Gracia A, et al. Among authors: chen ip. Nat Microbiol. 2020 Sep;5(9):1144-1157. doi: 10.1038/s41564-020-0742-9. Epub 2020 Jun 15. Nat Microbiol. 2020. PMID: 32541947 Free PMC article.
Turning up the heat on HIV-1.
Chen IP, Ott M. Chen IP, et al. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16109-16111. doi: 10.1073/pnas.2010212117. Epub 2020 Jun 30. Proc Natl Acad Sci U S A. 2020. PMID: 32606243 Free PMC article. No abstract available.
Rapid assessment of SARS-CoV-2-evolved variants using virus-like particles.
Syed AM, Taha TY, Tabata T, Chen IP, Ciling A, Khalid MM, Sreekumar B, Chen PY, Hayashi JM, Soczek KM, Ott M, Doudna JA. Syed AM, et al. Among authors: chen py, chen ip. Science. 2021 Dec 24;374(6575):1626-1632. doi: 10.1126/science.abl6184. Epub 2021 Nov 4. Science. 2021. PMID: 34735219 Free PMC article.
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
Walter M, Chen IP, Vallejo-Gracia A, Kim IJ, Bielska O, Lam VL, Hayashi JM, Cruz A, Shah S, Gross JD, Krogan NJ, Schilling B, Ott M, Verdin E. Walter M, et al. Among authors: chen ip. bioRxiv [Preprint]. 2022 Jan 5:2022.01.04.474979. doi: 10.1101/2022.01.04.474979. bioRxiv. 2022. PMID: 35018374 Free PMC article. Updated. Preprint.
Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination.
Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Gascon R, Tsou CL, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna JA, Ott M. Suryawanshi RK, et al. Among authors: chen py, chen ip. Nature. 2022 Jul;607(7918):351-355. doi: 10.1038/s41586-022-04865-0. Epub 2022 May 18. Nature. 2022. PMID: 35584773 Free PMC article.
Catching BETs by viruses.
Zandian M, Chen IP, Byrareddy SN, Fujimori DG, Ott M, Kutateladze TG. Zandian M, et al. Among authors: chen ip. Biochim Biophys Acta Gene Regul Mech. 2022 Oct;1865(7):194859. doi: 10.1016/j.bbagrm.2022.194859. Epub 2022 Aug 17. Biochim Biophys Acta Gene Regul Mech. 2022. PMID: 35985635 Free PMC article. Review.
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
Walter M, Chen IP, Vallejo-Gracia A, Kim IJ, Bielska O, Lam VL, Hayashi JM, Cruz A, Shah S, Soveg FW, Gross JD, Krogan NJ, Jerome KR, Schilling B, Ott M, Verdin E. Walter M, et al. Among authors: chen ip. PLoS Pathog. 2022 Sep 12;18(9):e1010811. doi: 10.1371/journal.ppat.1010811. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36095012 Free PMC article.
Viral Hijacking of BET Proteins.
Chen IP, Ott M. Chen IP, et al. Viruses. 2022 Oct 17;14(10):2274. doi: 10.3390/v14102274. Viruses. 2022. PMID: 36298829 Free PMC article. Review.
Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6.
Taha TY, Chen IP, Hayashi JM, Tabata T, Walcott K, Kimmerly GR, Syed AM, Ciling A, Suryawanshi RK, Martin HS, Bach BH, Tsou CL, Montano M, Khalid MM, Sreekumar BK, Renuka Kumar G, Wyman S, Doudna JA, Ott M. Taha TY, et al. Among authors: chen ip. Nat Commun. 2023 Apr 21;14(1):2308. doi: 10.1038/s41467-023-37787-0. Nat Commun. 2023. PMID: 37085489 Free PMC article.
108 results