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Patient-Derived Ovarian Cancer Organoids Mimic Clinical Response and Exhibit Heterogeneous Inter- and Intrapatient Drug Responses.
Cell Rep. 2020 Jun 16;31(11):107762. doi: 10.1016/j.celrep.2020.107762.
Cell Rep. 2020.
PMID: 32553164
Free article.
An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity.
Kopper O, de Witte CJ, Lõhmussaar K, Valle-Inclan JE, Hami N, Kester L, Balgobind AV, Korving J, Proost N, Begthel H, van Wijk LM, Revilla SA, Theeuwsen R, van de Ven M, van Roosmalen MJ, Ponsioen B, Ho VWH, Neel BG, Bosse T, Gaarenstroom KN, Vrieling H, Vreeswijk MPG, van Diest PJ, Witteveen PO, Jonges T, Bos JL, van Oudenaarden A, Zweemer RP, Snippert HJG, Kloosterman WP, Clevers H.
Kopper O, et al. Among authors: hami n.
Nat Med. 2019 May;25(5):838-849. doi: 10.1038/s41591-019-0422-6. Epub 2019 Apr 22.
Nat Med. 2019.
PMID: 31011202
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Diverse BRAF Gene Fusions Confer Resistance to EGFR-Targeted Therapy via Differential Modulation of BRAF Activity.
Stangl C, Post JB, van Roosmalen MJ, Hami N, Verlaan-Klink I, Vos HR, van Es RM, Koudijs MJ, Voest EE, Snippert HJG, Kloosterman WP.
Stangl C, et al. Among authors: hami n.
Mol Cancer Res. 2020 Apr;18(4):537-548. doi: 10.1158/1541-7786.MCR-19-0529. Epub 2020 Jan 7.
Mol Cancer Res. 2020.
PMID: 31911540
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Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids.
Bolhaqueiro ACF, Ponsioen B, Bakker B, Klaasen SJ, Kucukkose E, van Jaarsveld RH, Vivié J, Verlaan-Klink I, Hami N, Spierings DCJ, Sasaki N, Dutta D, Boj SF, Vries RGJ, Lansdorp PM, van de Wetering M, van Oudenaarden A, Clevers H, Kranenburg O, Foijer F, Snippert HJG, Kops GJPL.
Bolhaqueiro ACF, et al. Among authors: hami n.
Nat Genet. 2019 May;51(5):824-834. doi: 10.1038/s41588-019-0399-6. Epub 2019 Apr 29.
Nat Genet. 2019.
PMID: 31036964
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CRISPR-induced RASGAP deficiencies in colorectal cancer organoids reveal that only loss of NF1 promotes resistance to EGFR inhibition.
Post JB, Hami N, Mertens AEE, Elfrink S, Bos JL, Snippert HJG.
Post JB, et al. Among authors: hami n.
Oncotarget. 2019 Feb 15;10(14):1440-1457. doi: 10.18632/oncotarget.26677. eCollection 2019 Feb 15.
Oncotarget. 2019.
PMID: 30858928
Free PMC article.
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Interoperability optimization in healthcare collaboration networks.
Alrajeh NA, Elmir B, Bounabat B, El Hami N.
Alrajeh NA, et al. Among authors: el hami n.
Biomed Tech (Berl). 2012 Oct;57(5):403-11. doi: 10.1515/bmt-2011-0118.
Biomed Tech (Berl). 2012.
PMID: 25854667
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