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G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19.
da Rocha J, Othman H, Tiemessen CT, Botha G, Ramsay M, Masimirembwa C, Adebamowo C, Choudhury A, Brandenburg JT, Matshaba M, Simo G, Gamo FJ, Hazelhurst S; H3Africa Consortium. da Rocha J, et al. Among authors: hazelhurst s. medRxiv [Preprint]. 2020 Jun 2:2020.05.27.20114066. doi: 10.1101/2020.05.27.20114066. medRxiv. 2020. PMID: 32577690 Free PMC article. Updated. Preprint.
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans.
Choudhury A, Ramsay M, Hazelhurst S, Aron S, Bardien S, Botha G, Chimusa ER, Christoffels A, Gamieldien J, Sefid-Dashti MJ, Joubert F, Meintjes A, Mulder N, Ramesar R, Rees J, Scholtz K, Sengupta D, Soodyall H, Venter P, Warnich L, Pepper MS. Choudhury A, et al. Among authors: hazelhurst s. Nat Commun. 2017 Dec 12;8(1):2062. doi: 10.1038/s41467-017-00663-9. Nat Commun. 2017. PMID: 29233967 Free PMC article.
Novel and Known Gene-Smoking Interactions With cIMT Identified as Potential Drivers for Atherosclerosis Risk in West-African Populations of the AWI-Gen Study.
Boua PR, Brandenburg JT, Choudhury A, Hazelhurst S, Sengupta D, Agongo G, Nonterah EA, Oduro AR, Tinto H, Mathew CG, Sorgho H, Ramsay M. Boua PR, et al. Among authors: hazelhurst s. Front Genet. 2020 Feb 7;10:1354. doi: 10.3389/fgene.2019.01354. eCollection 2019. Front Genet. 2020. PMID: 32117412 Free PMC article.
Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: Similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism.
Othman H, Bouslama Z, Brandenburg JT, da Rocha J, Hamdi Y, Ghedira K, Srairi-Abid N, Hazelhurst S. Othman H, et al. Among authors: hazelhurst s. Biochem Biophys Res Commun. 2020 Jun 30;527(3):702-708. doi: 10.1016/j.bbrc.2020.05.028. Epub 2020 May 14. Biochem Biophys Res Commun. 2020. PMID: 32410735 Free PMC article.
High-depth African genomes inform human migration and health.
Choudhury A, Aron S, Botigué LR, Sengupta D, Botha G, Bensellak T, Wells G, Kumuthini J, Shriner D, Fakim YJ, Ghoorah AW, Dareng E, Odia T, Falola O, Adebiyi E, Hazelhurst S, Mazandu G, Nyangiri OA, Mbiyavanga M, Benkahla A, Kassim SK, Mulder N, Adebamowo SN, Chimusa ER, Muzny D, Metcalf G, Gibbs RA; TrypanoGEN Research Group; Rotimi C, Ramsay M; H3Africa Consortium; Adeyemo AA, Lombard Z, Hanchard NA. Choudhury A, et al. Among authors: hazelhurst s. Nature. 2020 Oct;586(7831):741-748. doi: 10.1038/s41586-020-2859-7. Epub 2020 Oct 28. Nature. 2020. PMID: 33116287 Free PMC article.
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