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159 results

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Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits.
Di Giovannantonio M, Harris BH, Zhang P, Kitchen-Smith I, Xiong L, Sahgal N, Stracquadanio G, Wallace M, Blagden S, Lord S, Harris D, Harris AHL, Buffa FM, Bond GL. Di Giovannantonio M, et al. Among authors: buffa fm. J Med Genet. 2021 Jun;58(6):392-399. doi: 10.1136/jmedgenet-2019-106799. Epub 2020 Jun 26. J Med Genet. 2021. PMID: 32591342 Free PMC article.
Gene expression and hypoxia in breast cancer.
Favaro E, Lord S, Harris AL, Buffa FM. Favaro E, et al. Among authors: buffa fm. Genome Med. 2011 Aug 26;3(8):55. doi: 10.1186/gm271. Genome Med. 2011. PMID: 21875443 Free PMC article.
Gene Expression Signatures as Biomarkers of Tumour Hypoxia.
Harris BH, Barberis A, West CM, Buffa FM. Harris BH, et al. Among authors: buffa fm. Clin Oncol (R Coll Radiol). 2015 Oct;27(10):547-60. doi: 10.1016/j.clon.2015.07.004. Epub 2015 Aug 14. Clin Oncol (R Coll Radiol). 2015. PMID: 26282471 Review.
Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment.
Mehta S, Hughes NP, Li S, Jubb A, Adams R, Lord S, Koumakis L, van Stiphout R, Padhani A, Makris A, Buffa FM, Harris AL. Mehta S, et al. Among authors: buffa fm. EBioMedicine. 2016 Aug;10:109-16. doi: 10.1016/j.ebiom.2016.07.017. Epub 2016 Jul 16. EBioMedicine. 2016. PMID: 27474395 Free PMC article.
Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma.
MacGregor TP, Carter R, Gillies RS, Findlay JM, Kartsonaki C, Castro-Giner F, Sahgal N, Wang LM, Chetty R, Maynard ND, Cazier JB, Buffa F, McHugh PJ, Tomlinson I, Middleton MR, Sharma RA. MacGregor TP, et al. Sci Rep. 2018 May 8;8(1):7265. doi: 10.1038/s41598-018-24232-2. Sci Rep. 2018. PMID: 29739952 Free PMC article. Clinical Trial.
Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Lord SR, Collins JM, Cheng WC, Haider S, Wigfield S, Gaude E, Fielding BA, Pinnick KE, Harjes U, Segaran A, Jha P, Hoefler G, Pollak MN, Thompson AM, Roy PG, English R, Adams RF, Frezza C, Buffa FM, Karpe F, Harris AL. Lord SR, et al. Among authors: buffa fm. Br J Cancer. 2020 Jan;122(2):258-265. doi: 10.1038/s41416-019-0665-5. Epub 2019 Dec 10. Br J Cancer. 2020. PMID: 31819193 Free PMC article. Clinical Trial.
The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer.
Walsh CA, Akrap N, Garre E, Magnusson Y, Harrison H, Andersson D, Jonasson E, Rafnsdottir S, Choudhry H, Buffa F, Ragoussis J, Ståhlberg A, Harris A, Landberg G. Walsh CA, et al. PLoS One. 2020 Jul 21;15(7):e0236187. doi: 10.1371/journal.pone.0236187. eCollection 2020. PLoS One. 2020. PMID: 32692762 Free PMC article.
Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non-Small Cell Lung Cancer.
Skwarski M, McGowan DR, Belcher E, Di Chiara F, Stavroulias D, McCole M, Derham JL, Chu KY, Teoh E, Chauhan J, O'Reilly D, Harris BHL, Macklin PS, Bull JA, Green M, Rodriguez-Berriguete G, Prevo R, Folkes LK, Campo L, Ferencz P, Croal PL, Flight H, Qi C, Holmes J, O'Connor JPB, Gleeson FV, McKenna WG, Harris AL, Bulte D, Buffa FM, Macpherson RE, Higgins GS. Skwarski M, et al. Among authors: buffa fm. Clin Cancer Res. 2021 May 1;27(9):2459-2469. doi: 10.1158/1078-0432.CCR-20-4128. Epub 2021 Feb 17. Clin Cancer Res. 2021. PMID: 33597271 Free PMC article.
159 results