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Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs.
Do C, Dumont ELP, Salas M, Castano A, Mujahed H, Maldonado L, Singh A, DaSilva-Arnold SC, Bhagat G, Lehman S, Christiano AM, Madhavan S, Nagy PL, Green PHR, Feinman R, Trimble C, Illsley NP, Marder K, Honig L, Monk C, Goy A, Chow K, Goldlust S, Kaptain G, Siegel D, Tycko B. Do C, et al. Genome Biol. 2020 Jun 29;21(1):153. doi: 10.1186/s13059-020-02059-3. Genome Biol. 2020. PMID: 32594908 Free PMC article.
Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models.
Mendioroz M, Do C, Jiang X, Liu C, Darbary HK, Lang CF, Lin J, Thomas A, Abu-Amero S, Stanier P, Temkin A, Yale A, Liu MM, Li Y, Salas M, Kerkel K, Capone G, Silverman W, Yu YE, Moore G, Wegiel J, Tycko B. Mendioroz M, et al. Among authors: do c. Genome Biol. 2015 Nov 25;16:263. doi: 10.1186/s13059-015-0827-6. Genome Biol. 2015. PMID: 26607552 Free PMC article.
Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.
Paliwal A, Temkin AM, Kerkel K, Yale A, Yotova I, Drost N, Lax S, Nhan-Chang CL, Powell C, Borczuk A, Aviv A, Wapner R, Chen X, Nagy PL, Schork N, Do C, Torkamani A, Tycko B. Paliwal A, et al. Among authors: do c. PLoS Genet. 2013 Aug;9(8):e1003622. doi: 10.1371/journal.pgen.1003622. Epub 2013 Aug 29. PLoS Genet. 2013. PMID: 24009515 Free PMC article.
Breast cancer family history and allele-specific DNA methylation in the legacy girls study.
Wu HC, Do C, Andrulis IL, John EM, Daly MB, Buys SS, Chung WK, Knight JA, Bradbury AR, Keegan THM, Schwartz L, Krupska I, Miller RL, Santella RM, Tycko B, Terry MB. Wu HC, et al. Among authors: do c. Epigenetics. 2018;13(3):240-250. doi: 10.1080/15592294.2018.1435243. Epub 2018 Apr 2. Epigenetics. 2018. PMID: 29436922 Free PMC article.
Genetic variants influence on the placenta regulatory landscape.
Delahaye F, Do C, Kong Y, Ashkar R, Salas M, Tycko B, Wapner R, Hughes F. Delahaye F, et al. Among authors: do c. PLoS Genet. 2018 Nov 19;14(11):e1007785. doi: 10.1371/journal.pgen.1007785. eCollection 2018 Nov. PLoS Genet. 2018. PMID: 30452450 Free PMC article.
DNA methylation patterns in T lymphocytes are generally stable in human pregnancies but CD3 methylation is associated with perinatal psychiatric symptoms.
Robakis TK, Lee S, Werner E, Liu G, Miller M, Wylie D, Champagne FA, Salas M, Do C, Tycko B, Monk C. Robakis TK, et al. Among authors: do c. Brain Behav Immun Health. 2020 Feb 18;3:100044. doi: 10.1016/j.bbih.2020.100044. eCollection 2020 Mar. Brain Behav Immun Health. 2020. PMID: 34589835 Free PMC article.
469 results