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Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs.
Do C, Dumont ELP, Salas M, Castano A, Mujahed H, Maldonado L, Singh A, DaSilva-Arnold SC, Bhagat G, Lehman S, Christiano AM, Madhavan S, Nagy PL, Green PHR, Feinman R, Trimble C, Illsley NP, Marder K, Honig L, Monk C, Goy A, Chow K, Goldlust S, Kaptain G, Siegel D, Tycko B. Do C, et al. Among authors: maldonado l. Genome Biol. 2020 Jun 29;21(1):153. doi: 10.1186/s13059-020-02059-3. Genome Biol. 2020. PMID: 32594908 Free PMC article.
Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile.
Kagohara LT, Schussel JL, Subbannayya T, Sahasrabuddhe N, Lebron C, Brait M, Maldonado L, Valle BL, Pirini F, Jahuira M, Lopez J, Letelier P, Brebi-Mieville P, Ili C, Pandey A, Chatterjee A, Sidransky D, Guerrero-Preston R. Kagohara LT, et al. Among authors: maldonado l. Future Oncol. 2015;11(2):233-49. doi: 10.2217/fon.14.165. Epub 2014 Jul 28. Future Oncol. 2015. PMID: 25066711 Free PMC article.
Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma.
Brait M, Munari E, LeBron C, Noordhuis MG, Begum S, Michailidi C, Gonzalez-Roibon N, Maldonado L, Sen T, Guerrero-Preston R, Cope L, Parrella P, Fazio VM, Ha PK, Netto GJ, Sidransky D, Hoque MO. Brait M, et al. Among authors: maldonado l. Cell Cycle. 2013 Apr 1;12(7):1058-70. doi: 10.4161/cc.24050. Epub 2013 Feb 22. Cell Cycle. 2013. PMID: 23435205 Free PMC article.
Association between lifestyle factors and CpG island methylation in a cancer-free population.
Brait M, Ford JG, Papaiahgari S, Garza MA, Lee JI, Loyo M, Maldonado L, Begum S, McCaffrey L, Howerton M, Sidransky D, Emerson MR, Ahmed S, Williams CD, Hoque MO. Brait M, et al. Among authors: maldonado l. Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2984-91. doi: 10.1158/1055-9965.EPI-08-1245. Epub 2009 Oct 27. Cancer Epidemiol Biomarkers Prev. 2009. PMID: 19861513 Free PMC article.
Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population.
Brebi P, Maldonado L, Noordhuis MG, Ili C, Leal P, Garcia P, Brait M, Ribas J, Michailidi C, Perez J, Soudry E, Tapia O, Guzman P, Muñoz S, Van Neste L, Van Criekinge W, Irizarry R, Sidransky D, Roa JC, Guerrero-Preston R. Brebi P, et al. Among authors: maldonado l. Epigenetics. 2014 Feb;9(2):308-17. doi: 10.4161/epi.27120. Epub 2013 Nov 15. Epigenetics. 2014. PMID: 24241165 Free PMC article.
Epigenomics and ovarian carcinoma.
Maldonado L, Hoque MO. Maldonado L, et al. Biomark Med. 2010 Aug;4(4):543-70. doi: 10.2217/bmm.10.72. Biomark Med. 2010. PMID: 20701443 Free PMC article. Review.
285 results