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Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs.
Do C, Dumont ELP, Salas M, Castano A, Mujahed H, Maldonado L, Singh A, DaSilva-Arnold SC, Bhagat G, Lehman S, Christiano AM, Madhavan S, Nagy PL, Green PHR, Feinman R, Trimble C, Illsley NP, Marder K, Honig L, Monk C, Goy A, Chow K, Goldlust S, Kaptain G, Siegel D, Tycko B. Do C, et al. Among authors: monk c. Genome Biol. 2020 Jun 29;21(1):153. doi: 10.1186/s13059-020-02059-3. Genome Biol. 2020. PMID: 32594908 Free PMC article.
Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation.
Do C, Lang CF, Lin J, Darbary H, Krupska I, Gaba A, Petukhova L, Vonsattel JP, Gallagher MP, Goland RS, Clynes RA, Dwork A, Kral JG, Monk C, Christiano AM, Tycko B. Do C, et al. Among authors: monk c. Am J Hum Genet. 2016 May 5;98(5):934-955. doi: 10.1016/j.ajhg.2016.03.027. Am J Hum Genet. 2016. PMID: 27153397 Free PMC article.
Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes.
Walsh K, McCormack CA, Webster R, Pinto A, Lee S, Feng T, Krakovsky HS, O'Grady SM, Tycko B, Champagne FA, Werner EA, Liu G, Monk C. Walsh K, et al. Among authors: monk c. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):23996-24005. doi: 10.1073/pnas.1905890116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611411 Free PMC article.
DNA methylation patterns in T lymphocytes are generally stable in human pregnancies but CD3 methylation is associated with perinatal psychiatric symptoms.
Robakis TK, Lee S, Werner E, Liu G, Miller M, Wylie D, Champagne FA, Salas M, Do C, Tycko B, Monk C. Robakis TK, et al. Among authors: monk c. Brain Behav Immun Health. 2020 Feb 18;3:100044. doi: 10.1016/j.bbih.2020.100044. eCollection 2020 Mar. Brain Behav Immun Health. 2020. PMID: 34589835 Free PMC article.
391 results