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Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs.
Do C, Dumont ELP, Salas M, Castano A, Mujahed H, Maldonado L, Singh A, DaSilva-Arnold SC, Bhagat G, Lehman S, Christiano AM, Madhavan S, Nagy PL, Green PHR, Feinman R, Trimble C, Illsley NP, Marder K, Honig L, Monk C, Goy A, Chow K, Goldlust S, Kaptain G, Siegel D, Tycko B. Do C, et al. Among authors: nagy pl. Genome Biol. 2020 Jun 29;21(1):153. doi: 10.1186/s13059-020-02059-3. Genome Biol. 2020. PMID: 32594908 Free PMC article.
Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.
Paliwal A, Temkin AM, Kerkel K, Yale A, Yotova I, Drost N, Lax S, Nhan-Chang CL, Powell C, Borczuk A, Aviv A, Wapner R, Chen X, Nagy PL, Schork N, Do C, Torkamani A, Tycko B. Paliwal A, et al. Among authors: nagy pl. PLoS Genet. 2013 Aug;9(8):e1003622. doi: 10.1371/journal.pgen.1003622. Epub 2013 Aug 29. PLoS Genet. 2013. PMID: 24009515 Free PMC article.
Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations.
Oberg JA, Glade Bender JL, Sulis ML, Pendrick D, Sireci AN, Hsiao SJ, Turk AT, Dela Cruz FS, Hibshoosh H, Remotti H, Zylber RJ, Pang J, Diolaiti D, Koval C, Andrews SJ, Garvin JH, Yamashiro DJ, Chung WK, Emerson SG, Nagy PL, Mansukhani MM, Kung AL. Oberg JA, et al. Among authors: nagy pl. Genome Med. 2016 Dec 23;8(1):133. doi: 10.1186/s13073-016-0389-6. Genome Med. 2016. PMID: 28007021 Free PMC article. Clinical Trial.
A case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma.
Dela Cruz FS, Diolaiti D, Turk AT, Rainey AR, Ambesi-Impiombato A, Andrews SJ, Mansukhani MM, Nagy PL, Alvarez MJ, Califano A, Forouhar F, Modzelewski B, Mitchell CM, Yamashiro DJ, Marks LJ, Glade Bender JL, Kung AL. Dela Cruz FS, et al. Among authors: nagy pl. Genome Med. 2016 Oct 31;8(1):116. doi: 10.1186/s13073-016-0366-0. Genome Med. 2016. PMID: 27799065 Free PMC article.
C9ORF72 repeat expansions not detected in a group of patients with schizophrenia.
Huey ED, Nagy PL, Rodriguez-Murillo L, Manoochehri M, Goldman J, Lieberman J, Karayiorgou M, Mayeux R. Huey ED, et al. Among authors: nagy pl. Neurobiol Aging. 2013 Apr;34(4):1309.e9-10. doi: 10.1016/j.neurobiolaging.2012.08.011. Epub 2012 Oct 1. Neurobiol Aging. 2013. PMID: 23036583 Free PMC article.
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