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OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance.
Yang Y, Li X, Luan HH, Zhang B, Zhang K, Nam JH, Li Z, Fu M, Munk A, Zhang D, Wang S, Liu Y, Albuquerque JP, Ong Q, Li R, Wang Q, Robert ME, Perry RJ, Chung D, Shulman GI, Yang X. Yang Y, et al. Among authors: shulman gi. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16616-16625. doi: 10.1073/pnas.1916121117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601203 Free PMC article.
Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo.
Hurov JB, Huang M, White LS, Lennerz J, Choi CS, Cho YR, Kim HJ, Prior JL, Piwnica-Worms D, Cantley LC, Kim JK, Shulman GI, Piwnica-Worms H. Hurov JB, et al. Among authors: shulman gi. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5680-5. doi: 10.1073/pnas.0701179104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372192 Free PMC article.
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome.
Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, Yonemitsu S, Cline GW, Befroy D, Zemany L, Kahn BB, Papademetris X, Rothman DL, Shulman GI. Petersen KF, et al. Among authors: shulman gi. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12587-94. doi: 10.1073/pnas.0705408104. Epub 2007 Jul 18. Proc Natl Acad Sci U S A. 2007. PMID: 17640906 Free PMC article.
Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity.
Choi CS, Savage DB, Abu-Elheiga L, Liu ZX, Kim S, Kulkarni A, Distefano A, Hwang YJ, Reznick RM, Codella R, Zhang D, Cline GW, Wakil SJ, Shulman GI. Choi CS, et al. Among authors: shulman gi. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16480-5. doi: 10.1073/pnas.0706794104. Epub 2007 Oct 8. Proc Natl Acad Sci U S A. 2007. PMID: 17923673 Free PMC article.
589 results