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A Pt(IV)-conjugated brain penetrant macrocyclic peptide shows pre-clinical efficacy in glioblastoma.
Jimenez-Macias JL, Lee YC, Miller E, Finkelberg T, Zdioruk M, Berger G, Farquhar CE, Nowicki MO, Cho CF, Fedeles BI, Loas A, Pentelute BL, Lawler SE. Jimenez-Macias JL, et al. Among authors: pentelute bl. J Control Release. 2022 Dec;352:623-636. doi: 10.1016/j.jconrel.2022.10.051. Epub 2022 Nov 4. J Control Release. 2022. PMID: 36349615 Free PMC article.
Organometallic palladium reagents for cysteine bioconjugation.
Vinogradova EV, Zhang C, Spokoyny AM, Pentelute BL, Buchwald SL. Vinogradova EV, et al. Among authors: pentelute bl. Nature. 2015 Oct 29;526(7575):687-91. doi: 10.1038/nature15739. Nature. 2015. PMID: 26511579 Free PMC article.
Palladium-Mediated Arylation of Lysine in Unprotected Peptides.
Lee HG, Lautrette G, Pentelute BL, Buchwald SL. Lee HG, et al. Among authors: pentelute bl. Angew Chem Int Ed Engl. 2017 Mar 13;56(12):3177-3181. doi: 10.1002/anie.201611202. Epub 2017 Feb 16. Angew Chem Int Ed Engl. 2017. PMID: 28206688 Free PMC article.
Arylation Chemistry for Bioconjugation.
Zhang C, Vinogradova EV, Spokoyny AM, Buchwald SL, Pentelute BL. Zhang C, et al. Among authors: pentelute bl. Angew Chem Int Ed Engl. 2019 Apr 1;58(15):4810-4839. doi: 10.1002/anie.201806009. Epub 2019 Feb 15. Angew Chem Int Ed Engl. 2019. PMID: 30399206 Free PMC article. Review.
151 results