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Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins.
Tranter D, Paatero AO, Kawaguchi S, Kazemi S, Serrill JD, Kellosalo J, Vogel WK, Richter U, Mattos DR, Wan X, Thornburg CC, Oishi S, McPhail KL, Ishmael JE, Paavilainen VO. Tranter D, et al. Among authors: thornburg cc. ACS Chem Biol. 2020 Aug 21;15(8):2125-2136. doi: 10.1021/acschembio.0c00325. Epub 2020 Jul 20. ACS Chem Biol. 2020. PMID: 32608972 Free PMC article.
NCI Program for Natural Product Discovery: A Publicly-Accessible Library of Natural Product Fractions for High-Throughput Screening.
Thornburg CC, Britt JR, Evans JR, Akee RK, Whitt JA, Trinh SK, Harris MJ, Thompson JR, Ewing TL, Shipley SM, Grothaus PG, Newman DJ, Schneider JP, Grkovic T, O'Keefe BR. Thornburg CC, et al. ACS Chem Biol. 2018 Sep 21;13(9):2484-2497. doi: 10.1021/acschembio.8b00389. Epub 2018 Jun 13. ACS Chem Biol. 2018. PMID: 29812901 Free PMC article.
National Cancer Institute (NCI) Program for Natural Products Discovery: Rapid Isolation and Identification of Biologically Active Natural Products from the NCI Prefractionated Library.
Grkovic T, Akee RK, Thornburg CC, Trinh SK, Britt JR, Harris MJ, Evans JR, Kang U, Ensel S, Henrich CJ, Gustafson KR, Schneider JP, O'Keefe BR. Grkovic T, et al. Among authors: thornburg cc. ACS Chem Biol. 2020 Apr 17;15(4):1104-1114. doi: 10.1021/acschembio.0c00139. Epub 2020 Apr 7. ACS Chem Biol. 2020. PMID: 32223208 Free PMC article.
Screen for New Antimicrobial Natural Products from the NCI Program for Natural Product Discovery Prefractionated Extract Library.
Martínez-Fructuoso L, Arends SJR, Freire VF, Evans JR, DeVries S, Peyser BD, Akee RK, Thornburg CC, Kumar R, Ensel S, Morgan GM, McConachie GD, Veeder N, Duncan LR, Grkovic T, O'Keefe BR. Martínez-Fructuoso L, et al. Among authors: thornburg cc. ACS Infect Dis. 2023 Jun 9;9(6):1245-1256. doi: 10.1021/acsinfecdis.3c00067. Epub 2023 May 10. ACS Infect Dis. 2023. PMID: 37163243 Free PMC article.
The NCI library of traditional Chinese medicinal plant extracts - Preliminary assessment of the NCI-60 activity and chemical profiling of selected species.
He M, Grkovic T, Evans JR, Thornburg CC, Akee RK, Thompson JR, Whitt JA, Harris MJ, Loyal JA, Britt JR, Jia L, White JD, Newman DJ, O'Keefe BR. He M, et al. Among authors: thornburg cc. Fitoterapia. 2019 Sep;137:104285. doi: 10.1016/j.fitote.2019.104285. Epub 2019 Aug 3. Fitoterapia. 2019. PMID: 31386897 Free PMC article.
Creating and screening natural product libraries.
Wilson BAP, Thornburg CC, Henrich CJ, Grkovic T, O'Keefe BR. Wilson BAP, et al. Among authors: thornburg cc. Nat Prod Rep. 2020 Jul 1;37(7):893-918. doi: 10.1039/c9np00068b. Epub 2020 Mar 18. Nat Prod Rep. 2020. PMID: 32186299 Free PMC article. Review.