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Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling.
Corsello SM, Nagari RT, Spangler RD, Rossen J, Kocak M, Bryan JG, Humeidi R, Peck D, Wu X, Tang AA, Wang VM, Bender SA, Lemire E, Narayan R, Montgomery P, Ben-David U, Garvie CW, Chen Y, Rees MG, Lyons NJ, McFarland JM, Wong BT, Wang L, Dumont N, O'Hearn PJ, Stefan E, Doench JG, Harrington CN, Greulich H, Meyerson M, Vazquez F, Subramanian A, Roth JA, Bittker JA, Boehm JS, Mader CC, Tsherniak A, Golub TR. Corsello SM, et al. Among authors: wang l, wang vm. Nat Cancer. 2020 Feb;1(2):235-248. doi: 10.1038/s43018-019-0018-6. Epub 2020 Jan 20. Nat Cancer. 2020. PMID: 32613204 Free PMC article.
Noncanonical open reading frames encode functional proteins essential for cancer cell survival.
Prensner JR, Enache OM, Luria V, Krug K, Clauser KR, Dempster JM, Karger A, Wang L, Stumbraite K, Wang VM, Botta G, Lyons NJ, Goodale A, Kalani Z, Fritchman B, Brown A, Alan D, Green T, Yang X, Jaffe JD, Roth JA, Piccioni F, Kirschner MW, Ji Z, Root DE, Golub TR. Prensner JR, et al. Among authors: wang vm. Nat Biotechnol. 2021 Jun;39(6):697-704. doi: 10.1038/s41587-020-00806-2. Epub 2021 Jan 28. Nat Biotechnol. 2021. PMID: 33510483 Free PMC article.
Guidelines for ex vivo mechanical testing of tendon.
Lake SP, Snedeker JG, Wang VM, Awad H, Screen HRC, Thomopoulos S. Lake SP, et al. Among authors: wang vm. J Orthop Res. 2023 Oct;41(10):2105-2113. doi: 10.1002/jor.25647. Epub 2023 Jun 26. J Orthop Res. 2023. PMID: 37312619 Review.
Glycan degradation promotes macroautophagy.
Baudot AD, Wang VM, Leach JD, O'Prey J, Long JS, Paulus-Hock V, Lilla S, Thomson DM, Greenhorn J, Ghaffar F, Nixon C, Helfrich MH, Strathdee D, Pratt J, Marchesi F, Zanivan S, Ryan KM. Baudot AD, et al. Among authors: wang vm. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2111506119. doi: 10.1073/pnas.2111506119. Epub 2022 Jun 22. Proc Natl Acad Sci U S A. 2022. PMID: 35737835 Free PMC article.
88 results