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Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca2+, and activate NFAT and Akt signaling.
Robinson P, Sparrow AJ, Patel S, Malinowska M, Reilly SN, Zhang YH, Casadei B, Watkins H, Redwood C. Robinson P, et al. Among authors: casadei b. Am J Physiol Heart Circ Physiol. 2020 Aug 1;319(2):H306-H319. doi: 10.1152/ajpheart.00272.2020. Epub 2020 Jul 3. Am J Physiol Heart Circ Physiol. 2020. PMID: 32618513 Free PMC article.
Preoperative atorvastatin treatment in CABG patients rapidly improves vein graft redox state by inhibition of Rac1 and NADPH-oxidase activity.
Antoniades C, Bakogiannis C, Tousoulis D, Reilly S, Zhang MH, Paschalis A, Antonopoulos AS, Demosthenous M, Miliou A, Psarros C, Marinou K, Sfyras N, Economopoulos G, Casadei B, Channon KM, Stefanadis C. Antoniades C, et al. Among authors: casadei b. Circulation. 2010 Sep 14;122(11 Suppl):S66-73. doi: 10.1161/CIRCULATIONAHA.109.927376. Circulation. 2010. PMID: 20837928 Clinical Trial.
339 results