Dopazo J - Search Results

1

Immune Cell Associations with Cancer Risk.

Palomero L, Galván-Femenía I, de Cid R, Espín R, Barnes DR, Cimba, Blommaert E, Gil-Gil M, Falo C, Stradella A, Ouchi D, Roso-Llorach A, Violan C, Peña-Chilet M, Dopazo J, Extremera AI, García-Valero M, Herranz C, Mateo F, Mereu E, Beesley J, Chenevix-Trench G, Roux C, Mak T, Brunet J, Hakem R, Gorrini C, Antoniou AC, Lázaro C, Pujana MA. Palomero L, et al. Among authors: dopazo j. iScience. 2020 Jul 24;23(7):101296. doi: 10.1016/j.isci.2020.101296. Epub 2020 Jun 20. iScience. 2020. PMID: 32622267 Free PMC article.

2

Exploring the link between germline and somatic genetic alterations in breast carcinogenesis.

Bonifaci N, Górski B, Masojć B, Wokołorczyk D, Jakubowska A, Dębniak T, Berenguer A, Serra Musach J, Brunet J, Dopazo J, Narod SA, Lubiński J, Lázaro C, Cybulski C, Pujana MA. Bonifaci N, et al. Among authors: dopazo j. PLoS One. 2010 Nov 22;5(11):e14078. doi: 10.1371/journal.pone.0014078. PLoS One. 2010. PMID: 21124932 Free PMC article.

3

Gene Expression Integration into Pathway Modules Reveals a Pan-Cancer Metabolic Landscape.

Cubuk C, Hidalgo MR, Amadoz A, Pujana MA, Mateo F, Herranz C, Carbonell-Caballero J, Dopazo J. Cubuk C, et al. Among authors: dopazo j. Cancer Res. 2018 Nov 1;78(21):6059-6072. doi: 10.1158/0008-5472.CAN-17-2705. Epub 2018 Aug 22. Cancer Res. 2018. PMID: 30135189 Free article.

4

Differential metabolic activity and discovery of therapeutic targets using summarized metabolic pathway models.

Çubuk C, Hidalgo MR, Amadoz A, Rian K, Salavert F, Pujana MA, Mateo F, Herranz C, Carbonell-Caballero J, Dopazo J. Çubuk C, et al. Among authors: dopazo j. NPJ Syst Biol Appl. 2019 Mar 1;5:7. doi: 10.1038/s41540-019-0087-2. eCollection 2019. NPJ Syst Biol Appl. 2019. PMID: 30854222 Free PMC article.

5

Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models.

Esteban-Medina M, Peña-Chilet M, Loucera C, Dopazo J. Esteban-Medina M, et al. Among authors: dopazo j. BMC Bioinformatics. 2019 Jul 2;20(1):370. doi: 10.1186/s12859-019-2969-0. BMC Bioinformatics. 2019. PMID: 31266445 Free PMC article.

6

Using mechanistic models for the clinical interpretation of complex genomic variation.

Peña-Chilet M, Esteban-Medina M, Falco MM, Rian K, Hidalgo MR, Loucera C, Dopazo J. Peña-Chilet M, et al. Among authors: dopazo j. Sci Rep. 2019 Dec 12;9(1):18937. doi: 10.1038/s41598-019-55454-7. Sci Rep. 2019. PMID: 31831811 Free PMC article.

7

Mechanistic Models of Signaling Pathways Reveal the Drug Action Mechanisms behind Gender-Specific Gene Expression for Cancer Treatments.

Çubuk C, Can FE, Peña-Chilet M, Dopazo J. Çubuk C, et al. Among authors: dopazo j. Cells. 2020 Jun 29;9(7):1579. doi: 10.3390/cells9071579. Cells. 2020. PMID: 32610626 Free PMC article.

8

Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection.

Loucera C, Esteban-Medina M, Rian K, Falco MM, Dopazo J, Peña-Chilet M. Loucera C, et al. Among authors: dopazo j. Signal Transduct Target Ther. 2020 Dec 11;5(1):290. doi: 10.1038/s41392-020-00417-y. Signal Transduct Target Ther. 2020. PMID: 33311438 Free PMC article. No abstract available.

9

Mechanistic modeling of the SARS-CoV-2 disease map.

Rian K, Esteban-Medina M, Hidalgo MR, Çubuk C, Falco MM, Loucera C, Gunyel D, Ostaszewski M, Peña-Chilet M, Dopazo J. Rian K, et al. Among authors: dopazo j. BioData Min. 2021 Jan 21;14(1):5. doi: 10.1186/s13040-021-00234-1. BioData Min. 2021. PMID: 33478554 Free PMC article.

10

A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways.

Garrido-Rodriguez M, Lopez-Lopez D, Ortuno FM, Peña-Chilet M, Muñoz E, Calzado MA, Dopazo J. Garrido-Rodriguez M, et al. Among authors: dopazo j. PLoS Comput Biol. 2021 Feb 11;17(2):e1008748. doi: 10.1371/journal.pcbi.1008748. eCollection 2021 Feb. PLoS Comput Biol. 2021. PMID: 33571195 Free PMC article.

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