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Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.
Nagai Y, Miyakawa N, Takuwa H, Hori Y, Oyama K, Ji B, Takahashi M, Huang XP, Slocum ST, DiBerto JF, Xiong Y, Urushihata T, Hirabayashi T, Fujimoto A, Mimura K, English JG, Liu J, Inoue KI, Kumata K, Seki C, Ono M, Shimojo M, Zhang MR, Tomita Y, Nakahara J, Suhara T, Takada M, Higuchi M, Jin J, Roth BL, Minamimoto T. Nagai Y, et al. Among authors: urushihata t. Nat Neurosci. 2020 Sep;23(9):1157-1167. doi: 10.1038/s41593-020-0661-3. Epub 2020 Jul 6. Nat Neurosci. 2020. PMID: 32632286
Changes in effective diffusivity for oxygen during neural activation and deactivation estimated from capillary diameter measured by two-photon laser microscope.
Ito H, Takuwa H, Tajima Y, Kawaguchi H, Urushihata T, Taniguchi J, Ikoma Y, Seki C, Ibaraki M, Masamoto K, Kanno I. Ito H, et al. Among authors: urushihata t. J Physiol Sci. 2017 Mar;67(2):325-330. doi: 10.1007/s12576-016-0466-z. Epub 2016 Jun 25. J Physiol Sci. 2017. PMID: 27344668 Free PMC article.
Selective Disruption of Inhibitory Synapses Leading to Neuronal Hyperexcitability at an Early Stage of Tau Pathogenesis in a Mouse Model.
Shimojo M, Takuwa H, Takado Y, Tokunaga M, Tsukamoto S, Minatohara K, Ono M, Seki C, Maeda J, Urushihata T, Minamihisamatsu T, Aoki I, Kawamura K, Zhang MR, Suhara T, Sahara N, Higuchi M. Shimojo M, et al. Among authors: urushihata t. J Neurosci. 2020 Apr 22;40(17):3491-3501. doi: 10.1523/JNEUROSCI.2880-19.2020. Epub 2020 Apr 7. J Neurosci. 2020. PMID: 32265258 Free PMC article.
MRS-measured glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice.
Takado Y, Takuwa H, Sampei K, Urushihata T, Takahashi M, Shimojo M, Uchida S, Nitta N, Shibata S, Nagashima K, Ochi Y, Ono M, Maeda J, Tomita Y, Sahara N, Near J, Aoki I, Shibata K, Higuchi M. Takado Y, et al. Among authors: urushihata t. J Cereb Blood Flow Metab. 2022 Jan;42(1):197-212. doi: 10.1177/0271678X211045449. Epub 2021 Sep 13. J Cereb Blood Flow Metab. 2022. PMID: 34515548 Free PMC article.
21 results