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Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.
Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC. Shaked I, et al. Nat Immunol. 2015 Dec;16(12):1228-34. doi: 10.1038/ni.3321. Epub 2015 Nov 2. Nat Immunol. 2015. PMID: 26523867 Free PMC article.
CD40 agonist-induced IL-12p40 potentiates hepatotoxicity.
Bonnans C, Thomas G, He W, Jung B, Chen W, Liao M, Heyen J, Buetow B, Pillai S, Matsumoto D, Chaparro-Riggers J, Salek-Ardakani S, Qu Y. Bonnans C, et al. J Immunother Cancer. 2020 May;8(1):e000624. doi: 10.1136/jitc-2020-000624. J Immunother Cancer. 2020. PMID: 32474414 Free PMC article.
Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody.
Al-Khami AA, Youssef S, Abdiche Y, Nguyen H, Chou J, Kimberlin CR, Chin SM, Kamperschroer C, Jessen B, Kern B, Budimir N, Dillon CP, Xu A, Clark JD, Chou J, Kraynov E, Rajpal A, Lin JC, Salek-Ardakani S. Al-Khami AA, et al. Mol Cancer Ther. 2020 Oct;19(10):2105-2116. doi: 10.1158/1535-7163.MCT-20-0093. Epub 2020 Aug 26. Mol Cancer Ther. 2020. PMID: 32847983
FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells.
Campos Carrascosa L, van Beek AA, de Ruiter V, Doukas M, Wei J, Fisher TS, Ching K, Yang W, van Loon K, Boor PPC, Rakké YS, Noordam L, Doornebosch P, Grünhagen D, Verhoef K, Polak WG, IJzermans JNM, Ni I, Yeung YA, Salek-Ardakani S, Sprengers D, Kwekkeboom J. Campos Carrascosa L, et al. J Immunother Cancer. 2020 Sep;8(2):e000816. doi: 10.1136/jitc-2020-000816. J Immunother Cancer. 2020. PMID: 32900860 Free PMC article.
EZH2 as a Regulator of CD8+ T Cell Fate and Function.
Stairiker CJ, Thomas GD, Salek-Ardakani S. Stairiker CJ, et al. Front Immunol. 2020 Oct 6;11:593203. doi: 10.3389/fimmu.2020.593203. eCollection 2020. Front Immunol. 2020. PMID: 33117406 Free PMC article. Review.
CD8+ T Cell Exhaustion in Cancer.
Dolina JS, Van Braeckel-Budimir N, Thomas GD, Salek-Ardakani S. Dolina JS, et al. Among authors: salek ardakani s. Front Immunol. 2021 Jul 20;12:715234. doi: 10.3389/fimmu.2021.715234. eCollection 2021. Front Immunol. 2021. PMID: 34354714 Free PMC article. Review.
83 results