Ottenhoff THM - Search Results

1

Combining host-derived biomarkers with patient characteristics improves signature performance in predicting tuberculosis treatment outcomes.

Sivakumaran D, Jenum S, Vaz M, Selvam S, Ottenhoff THM, Haks MC, Malherbe ST, Doherty TM, Ritz C, Grewal HMS. Sivakumaran D, et al. Among authors: ottenhoff thm. Commun Biol. 2020 Jul 9;3(1):359. doi: 10.1038/s42003-020-1087-x. Commun Biol. 2020. PMID: 32647325 Free PMC article.

2

Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations.

Hanekom WA, Dockrell HM, Ottenhoff TH, Doherty TM, Fletcher H, McShane H, Weichold FF, Hoft DF, Parida SK, Fruth UJ. Hanekom WA, et al. PLoS Med. 2008 Jul 1;5(7):e145. doi: 10.1371/journal.pmed.0050145. PLoS Med. 2008. PMID: 18597551 Free PMC article.

3

Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa.

Black GF, Thiel BA, Ota MO, Parida SK, Adegbola R, Boom WH, Dockrell HM, Franken KL, Friggen AH, Hill PC, Klein MR, Lalor MK, Mayanja H, Schoolnik G, Stanley K, Weldingh K, Kaufmann SH, Walzl G, Ottenhoff TH; GCGH Biomarkers for TB Consortium. Black GF, et al. Clin Vaccine Immunol. 2009 Aug;16(8):1203-12. doi: 10.1128/CVI.00111-09. Epub 2009 Jun 24. Clin Vaccine Immunol. 2009. PMID: 19553548 Free PMC article.

4

Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers.

van Dissel JT, Arend SM, Prins C, Bang P, Tingskov PN, Lingnau K, Nouta J, Klein MR, Rosenkrands I, Ottenhoff TH, Kromann I, Doherty TM, Andersen P. van Dissel JT, et al. Vaccine. 2010 Apr 30;28(20):3571-81. doi: 10.1016/j.vaccine.2010.02.094. Epub 2010 Mar 11. Vaccine. 2010. PMID: 20226890 Clinical Trial.

5

First in humans: a new molecularly defined vaccine shows excellent safety and strong induction of long-lived Mycobacterium tuberculosis-specific Th1-cell like responses.

Ottenhoff TH, Doherty TM, van Dissel JT, Bang P, Lingnau K, Kromann I, Andersen P. Ottenhoff TH, et al. Hum Vaccin. 2010 Dec;6(12):1007-15. doi: 10.4161/hv.6.12.13143. Epub 2010 Dec 1. Hum Vaccin. 2010. PMID: 21178394 Review.

6

Ag85B-ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection.

van Dissel JT, Soonawala D, Joosten SA, Prins C, Arend SM, Bang P, Tingskov PN, Lingnau K, Nouta J, Hoff ST, Rosenkrands I, Kromann I, Ottenhoff TH, Doherty TM, Andersen P. van Dissel JT, et al. Vaccine. 2011 Mar 3;29(11):2100-9. doi: 10.1016/j.vaccine.2010.12.135. Epub 2011 Jan 20. Vaccine. 2011. PMID: 21256189 Clinical Trial.

7

Identification of biomarkers for tuberculosis disease using a novel dual-color RT-MLPA assay.

Joosten SA, Goeman JJ, Sutherland JS, Opmeer L, de Boer KG, Jacobsen M, Kaufmann SH, Finos L, Magis-Escurra C, Ota MO, Ottenhoff TH, Haks MC. Joosten SA, et al. Genes Immun. 2012 Jan;13(1):71-82. doi: 10.1038/gene.2011.64. Epub 2011 Sep 29. Genes Immun. 2012. PMID: 21956656

8

Identification of probable early-onset biomarkers for tuberculosis disease progression.

Sutherland JS, Hill PC, Adetifa IM, de Jong BC, Donkor S, Joosten SA, Opmeer L, Haks MC, Ottenhoff TH, Adegbola RA, Ota MO. Sutherland JS, et al. PLoS One. 2011;6(9):e25230. doi: 10.1371/journal.pone.0025230. Epub 2011 Sep 23. PLoS One. 2011. PMID: 21966464 Free PMC article.

9

Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting.

Chegou NN, Black GF, Loxton AG, Stanley K, Essone PN, Klein MR, Parida SK, Kaufmann SH, Doherty TM, Friggen AH, Franken KL, Ottenhoff TH, Walzl G. Chegou NN, et al. BMC Infect Dis. 2012 Jan 20;12:10. doi: 10.1186/1471-2334-12-10. BMC Infect Dis. 2012. PMID: 22260319 Free PMC article.

10

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa.

Sutherland JS, Lalor MK, Black GF, Ambrose LR, Loxton AG, Chegou NN, Kassa D, Mihret A, Howe R, Mayanja-Kizza H, Gomez MP, Donkor S, Franken K, Hanekom W, Klein MR, Parida SK, Boom WH, Thiel BA, Crampin AC, Ota M, Walzl G, Ottenhoff TH, Dockrell HM, Kaufmann SH; GCGH Biomarkers for TB consortium. Sutherland JS, et al. PLoS One. 2013 Sep 10;8(9):e74080. doi: 10.1371/journal.pone.0074080. eCollection 2013. PLoS One. 2013. PMID: 24040170 Free PMC article.

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