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Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses.
Brumpton B, Sanderson E, Heilbron K, Hartwig FP, Harrison S, Vie GÅ, Cho Y, Howe LD, Hughes A, Boomsma DI, Havdahl A, Hopper J, Neale M, Nivard MG, Pedersen NL, Reynolds CA, Tucker-Drob EM, Grotzinger A, Howe L, Morris T, Li S; Within-family Consortium; 23andMe Research Team; Auton A, Windmeijer F, Chen WM, Bjørngaard JH, Hveem K, Willer C, Evans DM, Kaprio J, Davey Smith G, Åsvold BO, Hemani G, Davies NM. Brumpton B, et al. Among authors: howe l, howe ld. Nat Commun. 2020 Jul 14;11(1):3519. doi: 10.1038/s41467-020-17117-4. Nat Commun. 2020. PMID: 32665587 Free PMC article.
Genetic influences on trajectories of systolic blood pressure across childhood and adolescence.
Howe LD, Parmar PG, Paternoster L, Warrington NM, Kemp JP, Briollais L, Newnham JP, Timpson NJ, Smith GD, Ring SM, Evans DM, Tilling K, Pennell CE, Beilin LJ, Palmer LJ, Lawlor DA. Howe LD, et al. Circ Cardiovasc Genet. 2013 Dec;6(6):608-14. doi: 10.1161/CIRCGENETICS.113.000197. Epub 2013 Nov 7. Circ Cardiovasc Genet. 2013. PMID: 24200906 Free PMC article.
A genome-wide association study of body mass index across early life and childhood.
Warrington NM, Howe LD, Paternoster L, Kaakinen M, Herrala S, Huikari V, Wu YY, Kemp JP, Timpson NJ, St Pourcain B, Davey Smith G, Tilling K, Jarvelin MR, Pennell CE, Evans DM, Lawlor DA, Briollais L, Palmer LJ. Warrington NM, et al. Among authors: howe ld. Int J Epidemiol. 2015 Apr;44(2):700-12. doi: 10.1093/ije/dyv077. Epub 2015 May 7. Int J Epidemiol. 2015. PMID: 25953783 Free PMC article.
Associations of Y chromosomal haplogroups with cardiometabolic risk factors and subclinical vascular measures in males during childhood and adolescence.
O'Keeffe LM, Howe LD, Fraser A, Hughes AD, Wade KH, Anderson EL, Lawlor DA, Erzurumluoglu AM, Davey-Smith G, Rodriguez S, Stergiakouli E. O'Keeffe LM, et al. Among authors: howe ld. Atherosclerosis. 2018 Jul;274:94-103. doi: 10.1016/j.atherosclerosis.2018.04.027. Epub 2018 Apr 25. Atherosclerosis. 2018. PMID: 29753233 Free PMC article.
Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses.
Wade KH, Chiesa ST, Hughes AD, Chaturvedi N, Charakida M, Rapala A, Muthurangu V, Khan T, Finer N, Sattar N, Howe LD, Fraser A, Lawlor DA, Davey Smith G, Deanfield JE, Timpson NJ. Wade KH, et al. Among authors: howe ld. Circulation. 2018 Nov 13;138(20):2187-2201. doi: 10.1161/CIRCULATIONAHA.117.033278. Epub 2018 Jul 30. Circulation. 2018. PMID: 30524135 Free PMC article.
Associations of Body Mass and Fat Indexes With Cardiometabolic Traits.
Bell JA, Carslake D, O'Keeffe LM, Frysz M, Howe LD, Hamer M, Wade KH, Timpson NJ, Davey Smith G. Bell JA, et al. Among authors: howe ld. J Am Coll Cardiol. 2018 Dec 18;72(24):3142-3154. doi: 10.1016/j.jacc.2018.09.066. J Am Coll Cardiol. 2018. PMID: 30545453 Free PMC article.
209 results