Greasley PJ - Search Results

1

Dapagliflozin and Diuretic Use in Patients With Heart Failure and Reduced Ejection Fraction in DAPA-HF.

Jackson AM, Dewan P, Anand IS, Bělohlávek J, Bengtsson O, de Boer RA, Böhm M, Boulton DW, Chopra VK, DeMets DL, Docherty KF, Dukát A, Greasley PJ, Howlett JG, Inzucchi SE, Katova T, Køber L, Kosiborod MN, Langkilde AM, Lindholm D, Ljungman CEA, Martinez FA, O'Meara E, Sabatine MS, Sjöstrand M, Solomon SD, Tereshchenko S, Verma S, Jhund PS, McMurray JJV. Jackson AM, et al. Among authors: greasley pj. Circulation. 2020 Sep 15;142(11):1040-1054. doi: 10.1161/CIRCULATIONAHA.120.047077. Epub 2020 Jul 16. Circulation. 2020. PMID: 32673497 Free PMC article. Clinical Trial.

2

Co- and posttranslational modification of the alpha(1B)-adrenergic receptor: effects on receptor expression and function.

Björklöf K, Lundström K, Abuin L, Greasley PJ, Cotecchia S. Björklöf K, et al. Among authors: greasley pj. Biochemistry. 2002 Apr 2;41(13):4281-91. doi: 10.1021/bi015790j. Biochemistry. 2002. PMID: 11914074

3

Mutational and computational analysis of the alpha(1b)-adrenergic receptor. Involvement of basic and hydrophobic residues in receptor activation and G protein coupling.

Greasley PJ, Fanelli F, Scheer A, Abuin L, Nenniger-Tosato M, DeBenedetti PG, Cotecchia S. Greasley PJ, et al. J Biol Chem. 2001 Dec 7;276(49):46485-94. doi: 10.1074/jbc.M105791200. Epub 2001 Oct 3. J Biol Chem. 2001. PMID: 11585821 Free article.

4

The alpha1b-adrenergic receptor subtype: molecular properties and physiological implications.

Cotecchia S, Björklöf K, Rossier O, Stanasila L, Greasley P, Fanelli F. Cotecchia S, et al. J Recept Signal Transduct Res. 2002 Feb-Nov;22(1-4):1-16. doi: 10.1081/rrs-120014585. J Recept Signal Transduct Res. 2002. PMID: 12503605 Review.

5

Determinants of topogenesis and glycosylation of type II membrane proteins. Analysis of Na,K-ATPase beta 1 AND beta 3 subunits by glycosylation mapping.

Hasler U, Greasley PJ, von Heijne G, Geering K. Hasler U, et al. Among authors: greasley pj. J Biol Chem. 2000 Sep 15;275(37):29011-22. doi: 10.1074/jbc.M002867200. J Biol Chem. 2000. PMID: 10887183 Free article.

6

Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation.

Greasley PJ, Fanelli F, Rossier O, Abuin L, Cotecchia S. Greasley PJ, et al. Mol Pharmacol. 2002 May;61(5):1025-32. doi: 10.1124/mol.61.5.1025. Mol Pharmacol. 2002. PMID: 11961120

7

Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis.

Hallow KM, Helmlinger G, Greasley PJ, McMurray JJV, Boulton DW. Hallow KM, et al. Among authors: greasley pj. Diabetes Obes Metab. 2018 Mar;20(3):479-487. doi: 10.1111/dom.13126. Epub 2017 Nov 15. Diabetes Obes Metab. 2018. PMID: 29024278 Free article. Clinical Trial.

8

Evaluation of renal and cardiovascular protection mechanisms of SGLT2 inhibitors: model-based analysis of clinical data.

Hallow KM, Greasley PJ, Helmlinger G, Chu L, Heerspink HJ, Boulton DW. Hallow KM, et al. Among authors: greasley pj. Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1295-F1306. doi: 10.1152/ajprenal.00202.2018. Epub 2018 Jul 18. Am J Physiol Renal Physiol. 2018. PMID: 30019930 Free PMC article.

9

Effects of the sodium-glucose co-transporter-2 inhibitor dapagliflozin on estimated plasma volume in patients with type 2 diabetes.

Dekkers CCJ, Sjöström CD, Greasley PJ, Cain V, Boulton DW, Heerspink HJL. Dekkers CCJ, et al. Among authors: greasley pj. Diabetes Obes Metab. 2019 Dec;21(12):2667-2673. doi: 10.1111/dom.13855. Epub 2019 Sep 17. Diabetes Obes Metab. 2019. PMID: 31407856 Free PMC article. Clinical Trial.

10

Comparison of the urinary glucose excretion contributions of SGLT2 and SGLT1: A quantitative systems pharmacology analysis in healthy individuals and patients with type 2 diabetes treated with SGLT2 inhibitors.

Yakovleva T, Sokolov V, Chu L, Tang W, Greasley PJ, Peilot Sjögren H, Johansson S, Peskov K, Helmlinger G, Boulton DW, Penland RC. Yakovleva T, et al. Among authors: greasley pj. Diabetes Obes Metab. 2019 Dec;21(12):2684-2693. doi: 10.1111/dom.13858. Epub 2019 Sep 9. Diabetes Obes Metab. 2019. PMID: 31423699

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