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Clinical study protocol for a low-interventional study in intermediate age-related macular degeneration developing novel clinical endpoints for interventional clinical trials with a regulatory and patient access intention-MACUSTAR.
Terheyden JH, Holz FG, Schmitz-Valckenberg S, Lüning A, Schmid M, Rubin GS, Dunbar H, Tufail A, Crabb DP, Binns A, Sánchez CI, Hoyng C, Margaron P, Zakaria N, Durbin M, Luhmann U, Zamiri P, Cunha-Vaz J, Martinho C, Leal S, Finger RP; MACUSTAR consortium. Terheyden JH, et al. Among authors: dunbar h. Trials. 2020 Jul 18;21(1):659. doi: 10.1186/s13063-020-04595-6. Trials. 2020. PMID: 32682441 Free PMC article.
MACUSTAR: Development and Clinical Validation of Functional, Structural, and Patient-Reported Endpoints in Intermediate Age-Related Macular Degeneration.
Finger RP, Schmitz-Valckenberg S, Schmid M, Rubin GS, Dunbar H, Tufail A, Crabb DP, Binns A, Sánchez CI, Margaron P, Normand G, Durbin MK, Luhmann UFO, Zamiri P, Cunha-Vaz J, Asmus F, Holz FG; on behalf of the MACUSTAR consortium. Finger RP, et al. Among authors: dunbar h. Ophthalmologica. 2019;241(2):61-72. doi: 10.1159/000491402. Epub 2018 Aug 28. Ophthalmologica. 2019. PMID: 30153664 Free PMC article. Review.
Use of Composite End Points in Early and Intermediate Age-Related Macular Degeneration Clinical Trials: State-of-the-Art and Future Directions.
Terheyden JH, Schmitz-Valckenberg S, Crabb DP, Dunbar H, Luhmann UFO, Behning C, Schmid M, Silva R, Cunha-Vaz J, Tufail A, Weissgerber G, Leal S, Holz FG, Finger RP; on behalf of the MACUSTAR Consortium. Terheyden JH, et al. Among authors: dunbar h. Ophthalmologica. 2021;244(5):387-395. doi: 10.1159/000513591. Epub 2020 Dec 7. Ophthalmologica. 2021. PMID: 33285549 Free article. Review.
Repeatability and Discriminatory Power of Chart-Based Visual Function Tests in Individuals With Age-Related Macular Degeneration: A MACUSTAR Study Report.
Dunbar HMP, Behning C, Abdirahman A, Higgins BE, Binns AM, Terheyden JH, Zakaria N, Poor S, Finger RP, Leal S, Holz FG, Schmid M, Crabb DP, Rubin GS, Luhmann UFO; MACUSTAR Consortium. Dunbar HMP, et al. JAMA Ophthalmol. 2022 Aug 1;140(8):780-789. doi: 10.1001/jamaophthalmol.2022.2113. JAMA Ophthalmol. 2022. PMID: 35737401 Free PMC article.
Test-Retest Variability and Discriminatory Power of Measurements From Microperimetry and Dark Adaptation Assessment in People With Intermediate Age-Related Macular Degeneration - A MACUSTAR Study Report.
Higgins BE, Montesano G, Dunbar HMP, Binns AM, Taylor DJ, Behning C, Abdirahman A, Schmid MC, Terheyden JH, Zakaria N, Poor S, Finger RP, Leal S, Holz FG, Rubin GS, Luhmann UFO, Crabb DP; MACUSTAR Consortium. Higgins BE, et al. Among authors: dunbar hmp. Transl Vis Sci Technol. 2023 Jul 3;12(7):19. doi: 10.1167/tvst.12.7.19. Transl Vis Sci Technol. 2023. PMID: 37477933 Free PMC article.
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