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Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors.
Sci Rep. 2020 Jul 20;10(1):11933. doi: 10.1038/s41598-020-68890-7.
Sci Rep. 2020.
PMID: 32686739
Free PMC article.
ECSIT is essential for RANKL-induced stimulation of mitochondria in osteoclasts and a target for the anti-osteoclastogenic effects of estrogens.
Marques-Carvalho A, Sardão VA, Kim HN, Almeida M.
Marques-Carvalho A, et al.
Front Endocrinol (Lausanne). 2023 Apr 20;14:1110369. doi: 10.3389/fendo.2023.1110369. eCollection 2023.
Front Endocrinol (Lausanne). 2023.
PMID: 37152948
Free PMC article.
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The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice.
Warren A, Porter RM, Reyes-Castro O, Ali MM, Marques-Carvalho A, Kim HN, Gatrell LB, Schipani E, Nookaew I, O'Brien CA, Morello R, Almeida M.
Warren A, et al. Among authors: marques carvalho a.
Nat Commun. 2023 Jun 17;14(1):3616. doi: 10.1038/s41467-023-39392-7.
Nat Commun. 2023.
PMID: 37330524
Free PMC article.
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SULFATION PATHWAYS: Potential benefits of a sulfated resveratrol derivative for topical application.
Correia-da-Silva M, Rocha V, Marques C, Deus CM, Marques-Carvalho A, Oliveira PJ, Palmeira A, Pinto M, Sousa E, Sousa Lobo JM, Almeida IF.
Correia-da-Silva M, et al. Among authors: marques carvalho a.
J Mol Endocrinol. 2018 Aug;61(2):M27-M39. doi: 10.1530/JME-18-0031. Epub 2018 Mar 27.
J Mol Endocrinol. 2018.
PMID: 29588426
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Oestradiol and osteoclast differentiation: Effects on p53 and mitochondrial metabolism.
Marques-Carvalho A, Silva B, Pereira FB, Kim HN, Almeida M, Sardão VA.
Marques-Carvalho A, et al.
Eur J Clin Invest. 2024 Jun;54(6):e14195. doi: 10.1111/eci.14195. Epub 2024 Mar 22.
Eur J Clin Invest. 2024.
PMID: 38519718
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The role of reactive oxygen species in bone cell physiology and pathophysiology.
Marques-Carvalho A, Kim HN, Almeida M.
Marques-Carvalho A, et al.
Bone Rep. 2023 Feb 24;19:101664. doi: 10.1016/j.bonr.2023.101664. eCollection 2023 Dec.
Bone Rep. 2023.
PMID: 38163012
Free PMC article.
Review.
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