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The CYB5R3c .350C>G and G6PD A alleles modify severity of anemia in malaria and sickle cell disease.
Gordeuk VR, Shah BN, Zhang X, Thuma PE, Zulu S, Moono R, Reading NS, Song J, Zhang Y, Nouraie M, Campbell A, Minniti CP, Rana SR, Darbari DS, Kato GJ, Niu M, Castro OL, Machado R, Gladwin MT, Prchal JT. Gordeuk VR, et al. Among authors: zhang x, zhang y. Am J Hematol. 2020 Nov;95(11):1269-1279. doi: 10.1002/ajh.25941. Epub 2020 Sep 23. Am J Hematol. 2020. PMID: 32697331 Free PMC article. Clinical Trial.
Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease.
Zhang X, Zhang W, Ma SF, Desai AA, Saraf S, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Abbasi T, Casanova NG, Steinberg MH, Baldwin CT, Sebastiani P, Prchal JT, Kittles R, Garcia JG, Machado RF, Gordeuk VR. Zhang X, et al. Among authors: zhang w. Circulation. 2014 Apr 22;129(16):1650-8. doi: 10.1161/CIRCULATIONAHA.113.005296. Epub 2014 Feb 10. Circulation. 2014. PMID: 24515990 Free PMC article.
Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease.
Zhang X, Zhang W, Saraf SL, Nouraie M, Han J, Gowhari M, Hassan J, Miasnikova G, Sergueeva A, Nekhai S, Kittles R, Machado RF, Garcia JG, Gladwin MT, Steinberg MH, Sebastiani P, McClain DA, Gordeuk VR. Zhang X, et al. Among authors: zhang w. Hum Genet. 2015 Aug;134(8):895-904. doi: 10.1007/s00439-015-1572-3. Epub 2015 May 30. Hum Genet. 2015. PMID: 26025476 Free PMC article.
Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy.
Saraf SL, Zhang X, Shah B, Kanias T, Gudehithlu KP, Kittles R, Machado RF, Arruda JA, Gladwin MT, Singh AK, Gordeuk VR. Saraf SL, et al. Among authors: zhang x. Haematologica. 2015 Oct;100(10):1275-84. doi: 10.3324/haematol.2015.124875. Epub 2015 Jul 23. Haematologica. 2015. PMID: 26206798 Free PMC article.
Patterns of opioid use in sickle cell disease.
Han J, Saraf SL, Zhang X, Gowhari M, Molokie RE, Hassan J, Alhandalous C, Jain S, Younge J, Abbasi T, Machado RF, Gordeuk VR. Han J, et al. Among authors: zhang x. Am J Hematol. 2016 Nov;91(11):1102-1106. doi: 10.1002/ajh.24498. Epub 2016 Aug 8. Am J Hematol. 2016. PMID: 27466799 Free PMC article.
APOL1, α-thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia.
Saraf SL, Shah BN, Zhang X, Han J, Tayo BO, Abbasi T, Ostrower A, Guzman E, Molokie RE, Gowhari M, Hassan J, Jain S, Cooper RS, Machado RF, Lash JP, Gordeuk VR. Saraf SL, et al. Among authors: zhang x. Haematologica. 2017 Jan;102(1):e1-e6. doi: 10.3324/haematol.2016.154153. Epub 2016 Sep 22. Haematologica. 2017. PMID: 27658436 Free PMC article. No abstract available.
Prospective study of thrombosis and thrombospondin-1 expression in Chuvash polycythemia.
Sergueeva A, Miasnikova G, Shah BN, Song J, Lisina E, Okhotin DJ, Nouraie M, Nekhai S, Ammosova T, Niu XM, Prchal JT, Zhang X, Gordeuk VR. Sergueeva A, et al. Among authors: zhang x. Haematologica. 2017 May;102(5):e166-e169. doi: 10.3324/haematol.2016.158170. Epub 2017 Jan 19. Haematologica. 2017. PMID: 28104701 Free PMC article. No abstract available.
Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2α) polymorphism lowers hemoglobin concentration in Tibetan highlanders.
Tashi T, Scott Reading N, Wuren T, Zhang X, Moore LG, Hu H, Tang F, Shestakova A, Lorenzo F, Burjanivova T, Koul P, Guchhait P, Wittwer CT, Julian CG, Shah B, Huff CD, Gordeuk VR, Prchal JT, Ge R. Tashi T, et al. Among authors: zhang x. J Mol Med (Berl). 2017 Jun;95(6):665-670. doi: 10.1007/s00109-017-1519-3. Epub 2017 Feb 23. J Mol Med (Berl). 2017. PMID: 28233034
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