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The CYB5R3c .350C>G and G6PD A alleles modify severity of anemia in malaria and sickle cell disease.
Gordeuk VR, Shah BN, Zhang X, Thuma PE, Zulu S, Moono R, Reading NS, Song J, Zhang Y, Nouraie M, Campbell A, Minniti CP, Rana SR, Darbari DS, Kato GJ, Niu M, Castro OL, Machado R, Gladwin MT, Prchal JT. Gordeuk VR, et al. Among authors: zhang x, zhang y. Am J Hematol. 2020 Nov;95(11):1269-1279. doi: 10.1002/ajh.25941. Epub 2020 Sep 23. Am J Hematol. 2020. PMID: 32697331 Free PMC article. Clinical Trial.
Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates.
Novelli EM, Kato GJ, Ragni MV, Zhang Y, Hildesheim ME, Nouraie M, Barge S, Meyer MP, Hassett AC, Gordeuk VR, Gladwin MT, Isenberg JS. Novelli EM, et al. Among authors: zhang y. Am J Hematol. 2012 Mar;87(3):326-30. doi: 10.1002/ajh.22274. Epub 2012 Feb 8. Am J Hematol. 2012. PMID: 22318901 Free PMC article.
The relationship between pulmonary emphysema and kidney function in smokers.
Chandra D, Stamm JA, Palevsky PM, Leader JK, Fuhrman CR, Zhang Y, Bon J, Duncan SR, Branch RA, Weissfeld J, Gur D, Gladwin MT, Sciurba FC. Chandra D, et al. Among authors: zhang y. Chest. 2012 Sep;142(3):655-662. doi: 10.1378/chest.11-1456. Chest. 2012. PMID: 22459775 Free PMC article.
Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans.
Bae HT, Baldwin CT, Sebastiani P, Telen MJ, Ashley-Koch A, Garrett M, Hooper WC, Bean CJ, Debaun MR, Arking DE, Bhatnagar P, Casella JF, Keefer JR, Barron-Casella E, Gordeuk V, Kato GJ, Minniti C, Taylor J, Campbell A, Luchtman-Jones L, Hoppe C, Gladwin MT, Zhang Y, Steinberg MH. Bae HT, et al. Among authors: zhang y. Blood. 2012 Aug 30;120(9):1961-2. doi: 10.1182/blood-2012-06-432849. Blood. 2012. PMID: 22936743 Free PMC article. No abstract available.
The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe.
Nouraie M, Lee JS, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss TB, Zeng Q, Kato GJ, Gibbs JS, Hildesheim ME, Sachdev V, Barst RJ, Machado RF, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Goldsmith JC, Gordeuk VR, Gladwin MT; Walk-PHASST Investigators and Patients. Nouraie M, et al. Among authors: zhang y. Haematologica. 2013 Mar;98(3):464-72. doi: 10.3324/haematol.2012.068965. Epub 2012 Sep 14. Haematologica. 2013. PMID: 22983573 Free PMC article.
Genetic determinants of haemolysis in sickle cell anaemia.
Milton JN, Rooks H, Drasar E, McCabe EL, Baldwin CT, Melista E, Gordeuk VR, Nouraie M, Kato GR, Minniti C, Taylor J, Campbell A, Luchtman-Jones L, Rana S, Castro O, Zhang Y, Thein SL, Sebastiani P, Gladwin MT; Walk-PHAAST Investigators; Steinberg MH. Milton JN, et al. Among authors: zhang y. Br J Haematol. 2013 Apr;161(2):270-8. doi: 10.1111/bjh.12245. Epub 2013 Feb 14. Br J Haematol. 2013. PMID: 23406172 Free PMC article. Clinical Trial.
Red Blood Cells Store and Release Interleukin-33.
Wei J, Zhao J, Schrott V, Zhang Y, Gladwin M, Bullock G, Zhao Y. Wei J, et al. Among authors: zhang y. J Investig Med. 2015 Aug;63(6):806-10. doi: 10.1097/JIM.0000000000000213. J Investig Med. 2015. PMID: 26107423 Free PMC article.
Thrombospondin-1 gene polymorphism is associated with estimated pulmonary artery pressure in patients with sickle cell anemia.
Jacob SA, Novelli EM, Isenberg JS, Garrett ME, Chu Y, Soldano K, Ataga KI, Telen MJ, Ashley-Koch A, Gladwin MT, Zhang Y, Kato GJ. Jacob SA, et al. Among authors: zhang y. Am J Hematol. 2017 Mar;92(3):E31-E34. doi: 10.1002/ajh.24635. Epub 2017 Feb 3. Am J Hematol. 2017. PMID: 28033687 Free PMC article. Clinical Trial. No abstract available.
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