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Systematic Chemogenetic Library Assembly.
Canham SM, Wang Y, Cornett A, Auld DS, Baeschlin DK, Patoor M, Skaanderup PR, Honda A, Llamas L, Wendel G, Mapa FA, Aspesi P Jr, Labbé-Giguère N, Gamber GG, Palacios DS, Schuffenhauer A, Deng Z, Nigsch F, Frederiksen M, Bushell SM, Rothman D, Jain RK, Hemmerle H, Briner K, Porter JA, Tallarico JA, Jenkins JL. Canham SM, et al. Among authors: deng z. Cell Chem Biol. 2020 Sep 17;27(9):1124-1129. doi: 10.1016/j.chembiol.2020.07.004. Epub 2020 Jul 23. Cell Chem Biol. 2020. PMID: 32707038 Free article. Review.
Which aspects of HTS are empirically correlated with downstream success?
Bender A, Bojanic D, Davies JW, Crisman TJ, Mikhailov D, Scheiber J, Jenkins JL, Deng Z, Hill WA, Popov M, Jacoby E, Glick M. Bender A, et al. Among authors: deng z. Curr Opin Drug Discov Devel. 2008 May;11(3):327-37. Curr Opin Drug Discov Devel. 2008. PMID: 18428086 Review.
Flexible 3D pharmacophores as descriptors of dynamic biological space.
Nettles JH, Jenkins JL, Williams C, Clark AM, Bender A, Deng Z, Davies JW, Glick M. Nettles JH, et al. Among authors: deng z. J Mol Graph Model. 2007 Oct;26(3):622-33. doi: 10.1016/j.jmgm.2007.02.005. Epub 2007 Mar 1. J Mol Graph Model. 2007. PMID: 17395510
Discovery and Characterization of Allosteric WNK Kinase Inhibitors.
Yamada K, Zhang JH, Xie X, Reinhardt J, Xie AQ, LaSala D, Kohls D, Yowe D, Burdick D, Yoshisue H, Wakai H, Schmidt I, Gunawan J, Yasoshima K, Yue QK, Kato M, Mogi M, Idamakanti N, Kreder N, Drueckes P, Pandey P, Kawanami T, Huang W, Yagi YI, Deng Z, Park HM. Yamada K, et al. Among authors: deng z. ACS Chem Biol. 2016 Dec 16;11(12):3338-3346. doi: 10.1021/acschembio.6b00511. Epub 2016 Oct 19. ACS Chem Biol. 2016. PMID: 27712055
A kinase-focused compound collection: compilation and screening strategy.
Sun D, Chuaqui C, Deng Z, Bowes S, Chin D, Singh J, Cullen P, Hankins G, Lee WC, Donnelly J, Friedman J, Josiah S. Sun D, et al. Among authors: deng z. Chem Biol Drug Des. 2006 Jun;67(6):385-94. doi: 10.1111/j.1747-0285.2006.00396.x. Chem Biol Drug Des. 2006. PMID: 16882313
8,060 results