Bassik MC - Search Results

1

Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities.

Kelly MR, Kostyrko K, Han K, Mooney NA, Jeng EE, Spees K, Dinh PT, Abbott KL, Gwinn DM, Sweet-Cordero EA, Bassik MC, Jackson PK. Kelly MR, et al. Among authors: bassik mc. Cancer Discov. 2020 Dec;10(12):1950-1967. doi: 10.1158/2159-8290.CD-19-1274. Epub 2020 Jul 29. Cancer Discov. 2020. PMID: 32727735 Free PMC article.

2

Single-molecule imaging reveals distinct elongation and frameshifting dynamics between frames of expanded RNA repeats in C9ORF72-ALS/FTD.

Latallo MJ, Wang S, Dong D, Nelson B, Livingston NM, Wu R, Zhao N, Stasevich TJ, Bassik MC, Sun S, Wu B. Latallo MJ, et al. Among authors: bassik mc. Nat Commun. 2023 Sep 11;14(1):5581. doi: 10.1038/s41467-023-41339-x. Nat Commun. 2023. PMID: 37696852 Free PMC article.

3

E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia.

Duque-Afonso J, Lin CH, Han K, Wei MC, Feng J, Kurzer JH, Schneidawind C, Wong SH, Bassik MC, Cleary ML. Duque-Afonso J, et al. Among authors: bassik mc. Cancer Res. 2016 Dec 1;76(23):6937-6949. doi: 10.1158/0008-5472.CAN-16-1899. Epub 2016 Oct 7. Cancer Res. 2016. PMID: 27758892 Free PMC article.

4

Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.

Hess GT, Frésard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC. Hess GT, et al. Among authors: bassik mc. Nat Methods. 2016 Dec;13(12):1036-1042. doi: 10.1038/nmeth.4038. Epub 2016 Oct 31. Nat Methods. 2016. PMID: 27798611 Free PMC article.

5

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC. Han K, et al. Among authors: bassik mc. Nat Biotechnol. 2017 May;35(5):463-474. doi: 10.1038/nbt.3834. Epub 2017 Mar 20. Nat Biotechnol. 2017. PMID: 28319085 Free PMC article.

6

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens.

Morgens DW, Wainberg M, Boyle EA, Ursu O, Araya CL, Tsui CK, Haney MS, Hess GT, Han K, Jeng EE, Li A, Snyder MP, Greenleaf WJ, Kundaje A, Bassik MC. Morgens DW, et al. Among authors: bassik mc. Nat Commun. 2017 May 5;8:15178. doi: 10.1038/ncomms15178. Nat Commun. 2017. PMID: 28474669 Free PMC article.

7

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

Breslow DK, Hoogendoorn S, Kopp AR, Morgens DW, Vu BK, Kennedy MC, Han K, Li A, Hess GT, Bassik MC, Chen JK, Nachury MV. Breslow DK, et al. Among authors: bassik mc. Nat Genet. 2018 Mar;50(3):460-471. doi: 10.1038/s41588-018-0054-7. Epub 2018 Feb 19. Nat Genet. 2018. PMID: 29459677 Free PMC article.

8

KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics.

Milic B, Chakraborty A, Han K, Bassik MC, Block SM. Milic B, et al. Among authors: bassik mc. Proc Natl Acad Sci U S A. 2018 May 15;115(20):E4613-E4622. doi: 10.1073/pnas.1801242115. Epub 2018 Apr 27. Proc Natl Acad Sci U S A. 2018. PMID: 29703754 Free PMC article.

9

CBP Modulates Sensitivity to Dasatinib in Pre-BCR⁺ Acute Lymphoblastic Leukemia.

Duque-Afonso J, Lin CH, Han K, Morgens DW, Jeng EE, Weng Z, Jeong J, Wong SHK, Zhu L, Wei MC, Chae HD, Schrappe M, Cario G, Duyster J, Xiao X, Sakamoto KM, Bassik MC, Cleary ML. Duque-Afonso J, et al. Among authors: bassik mc. Cancer Res. 2018 Nov 15;78(22):6497-6508. doi: 10.1158/0008-5472.CAN-18-1703. Epub 2018 Sep 27. Cancer Res. 2018. PMID: 30262461 Free PMC article.

10

Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements.

Tycko J, Wainberg M, Marinov GK, Ursu O, Hess GT, Ego BK, Aradhana, Li A, Truong A, Trevino AE, Spees K, Yao D, Kaplow IM, Greenside PG, Morgens DW, Phanstiel DH, Snyder MP, Bintu L, Greenleaf WJ, Kundaje A, Bassik MC. Tycko J, et al. Among authors: bassik mc. Nat Commun. 2019 Sep 6;10(1):4063. doi: 10.1038/s41467-019-11955-7. Nat Commun. 2019. PMID: 31492858 Free PMC article.

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