Cheng SH - Search Results

1

Substrate reduction therapy using Genz-667161 reduces levels of pathogenic components in a mouse model of neuronopathic forms of Gaucher disease.

Blumenreich S, Yaacobi C, Vardi A, Barav OB, Vitner EB, Park H, Wang B, Cheng SH, Sardi SP, Futerman AH. Blumenreich S, et al. Among authors: cheng sh. J Neurochem. 2021 Mar;156(5):692-701. doi: 10.1111/jnc.15136. Epub 2020 Sep 12. J Neurochem. 2021. PMID: 32743826 Free article.

2

Sardi SP, Cheng SH, Shihabuddin LS. Sardi SP, et al. Among authors: cheng sh. Prog Neurobiol. 2015 Feb;125:47-62. doi: 10.1016/j.pneurobio.2014.12.001. Epub 2015 Jan 6. Prog Neurobiol. 2015. PMID: 25573151 Free article. Review.

3

CNS-accessible Inhibitor of Glucosylceramide Synthase for Substrate Reduction Therapy of Neuronopathic Gaucher Disease.

Marshall J, Sun Y, Bangari DS, Budman E, Park H, Nietupski JB, Allaire A, Cromwell MA, Wang B, Grabowski GA, Leonard JP, Cheng SH. Marshall J, et al. Among authors: cheng sh. Mol Ther. 2016 Jun;24(6):1019-1029. doi: 10.1038/mt.2016.53. Epub 2016 Mar 7. Mol Ther. 2016. PMID: 26948439 Free PMC article.

4

Substrate Reduction Therapy for Sandhoff Disease through Inhibition of Glucosylceramide Synthase Activity.

Marshall J, Nietupski JB, Park H, Cao J, Bangari DS, Silvescu C, Wilper T, Randall K, Tietz D, Wang B, Ying X, Leonard JP, Cheng SH. Marshall J, et al. Among authors: cheng sh. Mol Ther. 2019 Aug 7;27(8):1495-1506. doi: 10.1016/j.ymthe.2019.05.018. Epub 2019 Jun 4. Mol Ther. 2019. PMID: 31208914 Free PMC article.

5

Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models.

Sardi SP, Viel C, Clarke J, Treleaven CM, Richards AM, Park H, Olszewski MA, Dodge JC, Marshall J, Makino E, Wang B, Sidman RL, Cheng SH, Shihabuddin LS. Sardi SP, et al. Among authors: cheng sh. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2699-2704. doi: 10.1073/pnas.1616152114. Epub 2017 Feb 21. Proc Natl Acad Sci U S A. 2017. PMID: 28223512 Free PMC article.

6

Efficacy of Enzyme and Substrate Reduction Therapy with a Novel Antagonist of Glucosylceramide Synthase for Fabry Disease.

Ashe KM, Budman E, Bangari DS, Siegel CS, Nietupski JB, Wang B, Desnick RJ, Scheule RK, Leonard JP, Cheng SH, Marshall J. Ashe KM, et al. Among authors: cheng sh. Mol Med. 2015 Apr 30;21(1):389-99. doi: 10.2119/molmed.2015.00088. Mol Med. 2015. PMID: 25938659 Free PMC article.

7

Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models.

Sardi SP, Singh P, Cheng SH, Shihabuddin LS, Schlossmacher MG. Sardi SP, et al. Among authors: cheng sh. Neurodegener Dis. 2012;10(1-4):195-202. doi: 10.1159/000335038. Epub 2012 Feb 9. Neurodegener Dis. 2012. PMID: 22327140 Review.

8

Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson's disease.

Rockenstein E, Clarke J, Viel C, Panarello N, Treleaven CM, Kim C, Spencer B, Adame A, Park H, Dodge JC, Cheng SH, Shihabuddin LS, Masliah E, Sardi SP. Rockenstein E, et al. Among authors: cheng sh. Hum Mol Genet. 2016 Jul 1;25(13):2645-2660. doi: 10.1093/hmg/ddw124. Epub 2016 Apr 28. Hum Mol Genet. 2016. PMID: 27126635 Free PMC article.

9

Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer's disease.

Dodge JC, Tamsett TJ, Treleaven CM, Taksir TV, Piepenhagen P, Sardi SP, Cheng SH, Shihabuddin LS. Dodge JC, et al. Among authors: cheng sh. Alzheimers Res Ther. 2022 Feb 1;14(1):19. doi: 10.1186/s13195-022-00966-0. Alzheimers Res Ther. 2022. PMID: 35105352 Free PMC article.

10

Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.

Cullen V, Sardi SP, Ng J, Xu YH, Sun Y, Tomlinson JJ, Kolodziej P, Kahn I, Saftig P, Woulfe J, Rochet JC, Glicksman MA, Cheng SH, Grabowski GA, Shihabuddin LS, Schlossmacher MG. Cullen V, et al. Among authors: cheng sh. Ann Neurol. 2011 Jun;69(6):940-53. doi: 10.1002/ana.22400. Epub 2011 Apr 6. Ann Neurol. 2011. PMID: 21472771

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

986 results

Search Page