Nhachi CFB - Search Results

1

A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: a study of HIV-infected Zimbabwean adolescents.

Ngara B, Zvada S, Chawana TD, Stray-Pedersen B, Nhachi CFB, Rusakaniko S. Ngara B, et al. Among authors: nhachi cfb. BMC Pharmacol Toxicol. 2020 Aug 3;21(1):58. doi: 10.1186/s40360-020-00437-y. BMC Pharmacol Toxicol. 2020. PMID: 32746923 Free PMC article. Clinical Trial.

2

Genetic variants of drug metabolizing enzymes and drug transporter (ABCB1) as possible biomarkers for adverse drug reactions in an HIV/AIDS cohort in Zimbabwe.

Dhoro M, Ngara B, Kadzirange G, Nhachi C, Masimirembwa C. Dhoro M, et al. Curr HIV Res. 2013 Sep;11(6):481-90. doi: 10.2174/1570162x113119990048. Curr HIV Res. 2013. PMID: 24517233

3

CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe.

Dhoro M, Zvada S, Ngara B, Nhachi C, Kadzirange G, Chonzi P, Masimirembwa C. Dhoro M, et al. BMC Pharmacol Toxicol. 2015 Mar 27;16:4. doi: 10.1186/s40360-015-0004-2. BMC Pharmacol Toxicol. 2015. PMID: 25889207 Free PMC article.

4

Evaluating an enhanced adherence intervention among HIV positive adolescents failing atazanavir/ritonavir-based second line antiretroviral treatment at a public health clinic.

Chawana TD, Katzenstein D, Nathoo K, Ngara B, Nhachi CFB. Chawana TD, et al. Among authors: nhachi cfb. J AIDS HIV Res. 2017 Jan;9(1):17-30. doi: 10.5897/JAHR2016.0406. Epub 2017 Jan 31. J AIDS HIV Res. 2017. PMID: 31649827 Free PMC article.

5

Short Communication: Higher Tenofovir Concentrations in Hair Are Associated with Decreases in Viral Load and Not Self-Reported Adherence in HIV-Infected Adolescents with Second-Line Virological Treatment Failure.

Chawana T, Nhachi C, Nathoo K, Ngara B, Okochi H, Louie A, Kuncze K, Katzenstein D, Metcalfe J, Gandhi M. Chawana T, et al. AIDS Res Hum Retroviruses. 2021 Oct;37(10):748-750. doi: 10.1089/AID.2020.0258. Epub 2021 Feb 24. AIDS Res Hum Retroviruses. 2021. PMID: 33499754 Free PMC article. Clinical Trial.

6

Pharmacokinetic-pharmacodynamic modelling of atazanavir in hair among adolescents on antiretroviral treatment in Zimbabwe.

Ngara B, Zvada S, Chawana TD, Nhachi CFB, Rusakaniko S. Ngara B, et al. Among authors: nhachi cfb. BMC Pharmacol Toxicol. 2021 May 24;22(1):29. doi: 10.1186/s40360-021-00497-8. BMC Pharmacol Toxicol. 2021. PMID: 34030726 Free PMC article. Clinical Trial.

7

High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe.

Nyakutira C, Röshammar D, Chigutsa E, Chonzi P, Ashton M, Nhachi C, Masimirembwa C. Nyakutira C, et al. Eur J Clin Pharmacol. 2008 Apr;64(4):357-65. doi: 10.1007/s00228-007-0412-3. Epub 2007 Dec 5. Eur J Clin Pharmacol. 2008. PMID: 18057928

8

The effect of ketoconazole on praziquantel pharmacokinetics and the role of CYP3A4 in the formation of X-OH-praziquantel and not 4-OH-praziquantel.

Nleya L, Thelingwani R, Li XQ, Cavallin E, Isin E, Nhachi C, Masimirembwa C. Nleya L, et al. Eur J Clin Pharmacol. 2019 Aug;75(8):1077-1087. doi: 10.1007/s00228-019-02663-8. Epub 2019 May 15. Eur J Clin Pharmacol. 2019. PMID: 31089768 Clinical Trial.

9

Clinically relevant enantiomer specific R- and S-praziquantel pharmacokinetic drug-drug interactions with efavirenz and ritonavir.

Mutiti CS, Kapungu NN, Kanji CR, Stadler N, Stingl J, Nhachi C, Hakim J, Masimirembwa C, Thelingwani RS. Mutiti CS, et al. Pharmacol Res Perspect. 2021 May;9(3):e00769. doi: 10.1002/prp2.769. Pharmacol Res Perspect. 2021. PMID: 33929078 Free PMC article.

10

Healthcare Professionals' Knowledge of Pharmacogenetics and Attitudes Towards Antimicrobial Utilization in Zambia: Implications for a Precision Medicine Approach to Reducing Antimicrobial Resistance.

Mufwambi W, Stingl J, Masimirembwa C, Manasa J, Nhachi C, Stadler N, Mwila C, Kalungia AC, Mukosha M, Mutiti CS, Kamoto A, Kaonga P, Godman B, Munkombwe D. Mufwambi W, et al. Front Pharmacol. 2021 Jan 12;11:551522. doi: 10.3389/fphar.2020.551522. eCollection 2020. Front Pharmacol. 2021. PMID: 33510634 Free PMC article.

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